Check your eligibility now & get in touch with a study center

CHECK ELIGIBILITY

Check your eligibility now & get in touch with a study center

CHECK ELIGIBILITY

Check your eligibility now & get in touch with a study center

CHECK ELIGIBILITY

Check your eligibility now & get in touch with a study center

CHECK ELIGIBILITY

Check your eligibility now & get in touch with a study center

CHECK ELIGIBILITY

Have you or your child been recently diagnosed

with type 1 diabetes?

What is type 1 diabetes?

Type 1 diabetes (T1D) happens when the body's immune system (the body’s natural defence) accidentally destroys the cells that make insulin in the pancreas (beta cells). As a result, insulin production becomes low and therefore sugar in the blood gets too high. People often find out they have T1D when they start to:

  • Feel very thirsty
  • Get tired easily
  • Lose weight without a reason
  • Urinate more frequently

People with type 1 diabetes need to take insulin every day for the rest of their lives. This helps keep their blood sugar at the right level.

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Stages of type 1 diabetes:

Very often, type 1 diabetes starts many years before symptoms appear and a patient is diagnosed. People may not have any signs of disease until most of their beta cells are no longer making insulin.

Stage 1
Start of beta cell destruction
  • Immune system starts attacking its own cells that make insulin
  • Many insulin-producing cells still work
  • Blood sugar stays normal, and there are no symptoms
  • Most people stay unaware of disease
Stage 2 
Most people still undiagnosed
  • More insulin-making cells are attacked and damaged
  • Fewer beta cells left over time
  • Blood sugar slightly increased, especially after meals
  • Patients unlikely to notice symptoms
Stage 3
Most people are diagnosed at this stage
  • More insulin-making cells are destroyed
  • Body cannot control blood sugar anymore
  • Signs of T1D appear
  • Person will eventually need insulin every day for life
Stage 4
Established diabetes
  • No or very few insulin making cells remain
  • More difficult to manage blood sugar levels
  • Long-term complications gradually develop

After being diagnosed with Type 1 Diabetes (T1D), some people experience what doctors call a "honeymoon period." During this time, your body might still make some insulin on its own. This can mean you might need fewer insulin shots and find it easier to manage your blood sugar levels. Doctors are looking into ways to make this honeymoon period last longer, as it could be helpful for people living with T1D.

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What is the study medication?

The study medication is a special form of protein that is expected to be able to prevent the immune system from destroying cells that produce insulin. Now, scientists can make these proteins in the laboratory to help treat many illnesses. This protein may save the insulin producing cells in the pancreas.

 

There is a chance that you will receive placebo. A placebo looks like the medicine being tested and is also given in the same way as the medication that is being studied, but it does not have any medicine in it.

 

If you are already on insulin, this will be continued.

 

Sanofi is currently conducting 3 different clinical studies aiming to preserve function of insulin producing cells in participants with a recent diagnosis of Stage 3 of T1D.

 

Check out if you are eligible for these studies and if there are participating site(s) near you.

What can you expect during the study?

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Close support of the medical team to oversee your condition and safety, including tests such as: Mixed meal tolerance tests, a form of standard liquid meal consumed to test how much insulin your body could make

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Continuous glucose monitoring to measure your blood sugar level

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Blood and urine tests

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Pregnancy test, if applicable

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Physical examinations including checking your height, weight, and vital signs

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Electrocardiogram test (2 of the 3 trials) (checks your heart's electrical activity using electrodes placed on your skin) 

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Electronic diary usage and questionnaires about how you feel

Is there a cost to participate?

There is no cost to participate. All study-related exams, medications and medical care are provided. There is no insurance required to take part in this study. You may be compensated for expense and travel.

Version 1.0, Approved 04/2025

Images property of Sanofi