A U.S. Registry of Eosinophilic Esophagitis Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

Study of Eosinophilic Esophagitis Treatment with Investigational Medication

Recruiting
12 years or above
All
Phase N/A
300 participants needed
53 Locations

Study Overview

This observational research study is to better understand patients with eosinophilic esophagitis (EoE) who have recently been prescribed DUPIXENT® (dupilumab). The purpose of this research study is to look at how DUPIXENT is used in normal care of patients with EoE.

Possible benefits to others include a better understanding of EoE and helping to inform research and clinical trial design leading to treatment decisions in this patient population going forward.

Patient questionnaires will measure the following:

  • How EoE makes one feel
  • EoE symptoms
  • How EoE affects quality-of-life
  • How EoE impacts aspects of daily life
  • How difficult it is to swallow
  • How EoE symptoms have changed throughout the study

Eligibility Criteria

You may be eligible for this study if you meet the following criteria:

  • Conditions: Eosinophilic Esophagitis (EoE)
  • Age: 12 years or above
  • Gender: All

Key Inclusion Criteria:

  1. Initiating treatment with DUPIXENT® for EoE according to the USPI
  2. Able to understand and complete registry-related questionnaires (including adolescents)

Key Exclusion Criteria:

  1. Patients who have a contraindication to DUPIXENT® according to the USPI
  2. Treatment with DUPIXENT® within the 6 months prior to the screening assessment
  3. Participation in an ongoing interventional study on or within 6 months of the baseline assessment. Once enrolled in registry, participation is allowed in other ongoing studies (at the discretion of the registry investigator)

NOTE: Other protocol defined inclusion/exclusion criteria apply

This study investigates eosinophilic esophagitis (EoE) and aims to observe how patients with EoE are treated with an investigational medication as part of their routine care.

Participants will complete questionnaires about their experience with EoE, including how it affects their symptoms, quality of life, and daily activities. These questionnaires will help researchers understand changes in symptoms over the course of the study.

  • Who can participate: Participants must be starting treatment with the investigational medication for EoE and be able to complete questionnaires. Those with a contraindication to the medication or who have used it in the past six months are excluded.
  • Study details: Participants will complete questionnaires about their EoE symptoms and how the condition affects their daily lives. This is an observational study, meaning participants will continue their usual care without changes to their treatment. An observational study is a type of research study where data is collected by observing participants receiving routine care, without changing their treatment, which may focus on people using specific medications or having certain conditions to better understand how treatments work.
Updated on 01 Dec 2025. Study ID: NCT06693531

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