This study investigates the effects of an investigational medication on adults with non-responsive celiac disease (NRCD). Celiac disease is a condition where the immune system reacts to gluten, a protein found in wheat, barley, and rye, causing damage to the small intestine. NRCD refers to cases where symptoms persist despite …
This study investigates the treatment of moderate-to-severe atopic dermatitis (AD) in participants aged 12 years and older. Atopic dermatitis is a chronic skin condition that causes itchy and inflamed skin. The purpose of this study is to see if participants who responded to an investigational medication in earlier studies can …
This study investigates the long-term safety and effectiveness of an investigational medication for people with moderate to severe atopic dermatitis (AD). Atopic dermatitis is a chronic skin condition that causes itchy and inflamed skin. Participants in this study must be 12 years or older and have had AD for at …
This study investigates the effects of an investigational medication on children aged 2 to under 6 years who have uncontrolled asthma or frequent severe wheezing. Asthma is a condition where the airways in the lungs become narrow and swollen, making it hard to breathe. Wheezing is a high-pitched sound made …
This study investigates the long-term safety and tolerability of an investigational medication in adults with different types of multiple sclerosis (MS), including relapsing MS (RMS), primary progressive MS (PPMS), and non-relapsing secondary progressive MS (NRSPMS). Multiple sclerosis is a condition where the immune system attacks the protective covering of nerves, …
This study investigates the effects of an investigational medication on adults with moderate to severe atopic dermatitis, a skin condition that causes itchy and inflamed skin. The purpose is to understand how this treatment can affect the symptoms of atopic dermatitis, which is a long-lasting condition that can significantly impact …
This study investigates the safety and effectiveness of an investigational medication for treating chronic graft-versus-host disease (cGVHD) in diverse populations. cGVHD is a condition that can occur after a stem cell or bone marrow transplant, where the donated cells attack the recipient's body. Participants in this study include Black or …
This study investigates the safety and tolerability of an investigational medication for Fabry Disease (FD). FD is a genetic disorder that affects the body's ability to break down a specific type of fat, leading to a buildup in the body's cells. The purpose of this study is to explore how …
This study investigates the safety, efficacy, and immune response of an investigational vaccine for acne. Acne vulgaris is a common skin condition that causes inflammation and affects many people worldwide, especially teenagers and young adults. The study will test different doses of the vaccine in adults aged 18 to 45 …
This study investigates the effects of investigational medications on primary focal segmental glomerulosclerosis (FSGS) and primary minimal change disease (MCD). FSGS and MCD are kidney disorders that cause damage to the filtering units of the kidneys, leading to proteinuria, which is the presence of excess protein in the urine. The …
