This study investigates the treatment of moderate-to-severe atopic dermatitis in participants aged 12 years and older. The purpose is to evaluate the efficacy and safety of an investigational medication given as a subcutaneous injection, compared to a placebo. Participants will continue using their topical corticosteroids (TCS) during the study. The …
This study investigates the efficacy and safety of an investigational medication in people with sickle-cell disease. The study consists of a 52-week double-blind period followed by an open-label extension period. Participants will be in the study for a total of 104 weeks, including both parts.Participants will undergo various procedures, including …
The purpose of this study is to investigate the long-term effects of an investigational medication on preventing lung function decline in adults with uncontrolled moderate to severe asthma. The study will last for a total of 3 years, following a screening and run-in period of about 4 weeks. Participants will …
This study investigates the effects of an investigational medication compared to a daily oral dose of another treatment in adults with relapsing forms of multiple sclerosis. The study will last at least 12 months for the last participant and could be up to 40 months or longer for the first …
This study investigates chronic graft versus host disease (cGVHD) in children who have undergone a stem cell or bone marrow transplant. The purpose of this study is to understand how the investigational medication works in children with moderate to severe cGVHD. Participants will be in the study for up to …
This study investigates the treatment of immune thrombocytopenia (ITP) in adults who did not respond to first-line treatments. The purpose is to evaluate the effects of a new investigational medication. Participants will be in the study for a total of 60 weeks. This includes a screening period of up to …
The purpose of this study is to investigate the effects of investigational medications on primary focal segmental glomerulosclerosis (FSGS) and primary minimal change disease (MCD) in participants aged 16 to 75 years. The study will last up to 76 weeks, and participants will be involved for this entire duration. FSGS …
This study investigates the efficacy and safety of an investigational medication in people with moderately to severely active Crohn's Disease. Participants will be part of a study lasting up to 35 weeks. This includes a screening period of up to 5 weeks, followed by a treatment duration of up to …
This study investigates the effects of an investigational medication on people with moderately to severely active Crohn's Disease. The purpose of this study is to evaluate how safe and effective the medication is over a long period. Participants will be in the study for up to 286 weeks, which includes …
This study investigates the effect of an investigational medication on airway inflammation in people with Chronic Obstructive Pulmonary Disease (COPD). Participants will be in the study for up to 40 weeks. During this time, the effects on airway resistance and remodeling, including mucus plugging, will be assessed to see if …
