This study investigates the effectiveness and safety of an investigational medication in treating adults with chronic pruritus of unknown origin (CPUO). Pruritus is a medical term for severe itching. The study includes two separate, similar investigations (Study A and Study B) involving adult participants aged 18 to 90 years. Participants …
This study investigates the effects of an investigational medication on people with moderately to severely active Ulcerative Colitis (UC) who have an eosinophilic phenotype. Ulcerative Colitis is a long-term condition that causes inflammation and ulcers in the digestive tract. The study is designed to compare the investigational medication with a …
This study investigates the safety and effectiveness of an investigational medication for people with moderate to severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes itchy and inflamed skin. The study is for those who have already participated in a previous trial involving this investigational medication. Participants …
This study investigates the safety and preliminary effectiveness of an investigational medication used alone or with other cancer treatments for adults with advanced solid tumors. Solid tumors are abnormal masses of tissue that usually do not contain cysts or liquid areas, and they can occur in different parts of the …
This study investigates the long-term safety and effects of an investigational medication in people with moderate to severe atopic dermatitis, a skin condition that causes itchy and inflamed skin patches. The study is open to participants 12 years and older who have this condition.Participants will receive the investigational medication for …
This study investigates the treatment of moderate to severe atopic dermatitis, a skin condition causing red, itchy, and inflamed skin. The study aims to evaluate the effectiveness and safety of an investigational medication given as an injection under the skin, compared to a placebo, in individuals aged 12 and older …
The purpose of this study is to investigate an investigational medication for adults with moderate-to-severe asthma. Asthma is a condition where the airways in the lungs become narrow, making it hard to breathe. This study aims to see how safe and effective the investigational medication is in the long term …
This study investigates the safety and effectiveness of different doses of an investigational medication compared to a placebo in people recently diagnosed with Type 1 Diabetes (T1D) who are on insulin treatment. Type 1 Diabetes is a condition where the body does not produce insulin, a hormone needed to control …
This study investigates the effects of an investigational medication as an add-on therapy for adults with moderate-to-severe asthma. Asthma is a condition where the airways in the lungs become inflamed and narrow, making it hard to breathe. The study aims to see how effective and safe the investigational medication is …
This study investigates the effects of an investigational medication on adults with moderate to severe atopic dermatitis (AD), a skin condition that causes itchy and inflamed skin. Participants who have not responded well to topical treatments or cannot use them will be considered for systemic therapy in this study.Participants will …