This study investigates the effects of an investigational medication on adults with moderate to severe atopic dermatitis (AD). Atopic dermatitis is a chronic skin condition characterized by itchy, inflamed skin. Participants in this study have AD that is not well controlled with topical treatments or cannot use such treatments and …
This study investigates the effects of an investigational medication on individuals with active Systemic Lupus Erythematosus (SLE). SLE is a chronic autoimmune disease where the immune system attacks healthy tissues, causing inflammation and damage. The study involves two arms: one receiving the investigational medication and the other receiving a placebo, …
This study investigates the safety and effects of an investigational medication in people with certain blood cancers, such as acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Blood cancers affect the blood, bone marrow, and lymph nodes. The study aims to understand how the investigational medication works in the body …
This study investigates the safety and effectiveness of an investigational medication for adults with metastatic cancer. Metastatic cancer is a type of cancer that has spread from its original site to other parts of the body. The study will look at how the investigational medication works alone or with other …
This study investigates the effects of an investigational medication on esophageal function and remodeling in adults with eosinophilic esophagitis (EoE). EoE is a condition where a type of white blood cell, called eosinophil, builds up in the esophagus, leading to inflammation and difficulty swallowing. The study aims to understand how …
This study investigates the effects of an investigational medication on airway inflammation in people with Chronic Obstructive Pulmonary Disease (COPD). COPD is a lung condition that makes it hard to breathe and is often caused by smoking. The study includes both former and current smokers aged 40 to 70 years. …
This study investigates the long-term safety of an investigational medication for individuals with multiple myeloma. Multiple myeloma is a type of cancer that affects plasma cells, which are a kind of white blood cell found in bone marrow. The purpose of this study is to provide continued access to the …
This study investigates the effects of an investigational medication on individuals with moderately to severely active Ulcerative Colitis (UC) who have an eosinophilic phenotype. Ulcerative Colitis is a long-term condition that causes inflammation and sores in the digestive tract, specifically affecting the innermost lining of the large intestine and rectum. …
This study investigates the effects of an investigational medication on patients with advanced cancer that cannot be removed by surgery or has spread to other parts of the body. The study is divided into two parts. Part 1 focuses on finding the right dose of the investigational medication, either given …
This study investigates the effects of an investigational medication compared to a standard therapy for adults with Alpha-1 Antitrypsin Deficiency (AATD) emphysema. AATD is a genetic condition that can lead to lung problems like emphysema, which is a type of chronic lung disease that causes breathing difficulties. The study aims …
