This study investigates the safety and preliminary effects of SAR445877, an investigational medication, in adults with advanced solid tumors that cannot be removed by surgery or have spread to other parts of the body. The study is divided into two parts. In Part 1, researchers will determine safe doses for …
This study investigates the long-term safety and how well an investigational medication works in people with moderate to severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes itchy and inflamed skin. The study is for participants who are 12 years or older.Participants will receive the investigational medication …
This study investigates the safety and efficacy of three different dose levels of an investigational medication compared to a placebo in people with newly diagnosed Type 1 Diabetes (T1D) who are on insulin treatment. Type 1 diabetes is a chronic disease where the body's defense system mistakenly attacks specific cells …
This study investigates the long-term safety and tolerability of an investigational medication in adults with different types of multiple sclerosis (MS), such as relapsing MS (RMS), primary progressive MS (PPMS), and non-relapsing secondary progressive MS (NRSPMS). Multiple sclerosis is a condition where the immune system mistakenly attacks the protective covering …
This study investigates the long-term safety and effects of an investigational medication in adults with Alpha-1 Antitrypsin Deficiency (AATD) emphysema. AATD is a genetic condition that can lead to lung diseases like emphysema. Emphysema is a lung condition that causes shortness of breath due to damaged air sacs in the …
This study investigates the effects of investigational medications on primary focal segmental glomerulosclerosis (FSGS) and primary minimal change disease (MCD). FSGS and MCD are kidney disorders that cause proteinuria, which is an excess of protein in the urine. The purpose of this study is to see how these investigational medications …
This study investigates the long-term safety and efficacy of an investigational medication in adults with moderate-to-severe asthma. Asthma is a condition where the airways in the lungs swell and narrow, making it hard to breathe. The participants in this study have already completed a previous study and will continue using …
This study investigates the effects of an investigational medication in patients with relapsed or refractory multiple myeloma (RRMM). Multiple myeloma is a type of cancer that affects plasma cells, which are a kind of white blood cell in the bone marrow. The purpose of the study is to find the …
This study investigates the safety and immune response to an investigational vaccine designed to prevent lower respiratory tract disease caused by human metapneumovirus (hMPV) and respiratory syncytial virus (RSV) in adults aged 60 years and older. The study aims to understand how well the vaccine works in creating an immune …
This study investigates the use of an investigational medication for erectile dysfunction. Erectile dysfunction is when someone has trouble getting or keeping an erection. The study will look at whether participants can properly choose and use the medication by following the instructions on the label and completing a health survey. …
