This study investigates the effects of combining investigational medication with other new treatments, with or without dexamethasone, for patients with relapsed or refractory myeloma. Myeloma is a type of blood cancer that affects plasma cells in the bone marrow. Relapsed or refractory means that the cancer has returned after treatment …
This study investigates the use of an investigational medication in patients who have undergone or will undergo a kidney transplant. The study focuses on a condition called antibody-mediated rejection (AMR), which can occur after a kidney transplant. AMR happens when the body's immune system attacks the new kidney. The study …
This study investigates the effectiveness and safety of an investigational medication for adults with moderate-to-severe rheumatoid arthritis (RA). RA is a condition where the immune system attacks the joints, causing pain and swelling. Participants in this study have RA that is not well-controlled with methotrexate and have not used certain …
This study investigates the effects of an investigational medication on adults with moderate to severe Hidradenitis Suppurativa (HS), a skin condition characterized by painful lumps under the skin. The purpose is to compare the investigational medication with a placebo to assess its efficacy and safety.Participants will be divided into three …
This study investigates the effects of an investigational medication compared to a placebo in people who have had a lung transplant and are experiencing a progressive condition called chronic lung allograft dysfunction (CLAD). CLAD is a condition that affects the lungs after a transplant, causing them to not work as …
This study investigates the effects of an investigational medication on individuals with non-cystic fibrosis bronchiectasis (NCFB). NCFB is a condition where the airways in the lungs become damaged, leading to symptoms like coughing and producing phlegm. The study will compare two different doses of the investigational medication to a placebo, …
This study investigates the effectiveness of an investigational medication compared to a placebo in treating pruritus, which is severe itching, in individuals with Lichen Simplex Chronicus (LSC). LSC is a skin condition characterized by thickened, itchy patches of skin. Participants will receive either the investigational medication through injections or a …
This study investigates the effects of an investigational medication on pruritus, a condition that causes severe itching, in patients with Lichen Simplex Chronicus (LSC). LSC is a skin disorder characterized by thickened, itchy patches of skin. The study will compare the investigational medication given by injection to a placebo, which …
This study investigates the effects of an investigational medication on chronic rhinosinusitis without nasal polyps (CRSsNP). CRSsNP is a condition where the nasal passages and sinuses are inflamed, causing symptoms like nasal congestion and facial pain. The study compares two different dosing regimens of the investigational medication to a placebo, …
This study investigates the safety and ability of an investigational pneumococcal vaccine to help the body produce antibodies. Antibodies are special proteins that help fight infections. The study compares this investigational vaccine with a licensed vaccine in infants who are around 2 months old.Participants will receive either the investigational vaccine …
