This study investigates the use of an investigational gene therapy for adults with phenylketonuria (PKU), a condition where the body cannot break down an amino acid called phenylalanine (Phe). The purpose of this study is to see if the investigational treatment can safely reduce Phe levels and allow participants to …
This study investigates the effects of an investigational medication compared to a placebo in adults aged 18 to 70 with active Systemic Lupus Erythematosus (SLE). SLE is a chronic autoimmune disease where the immune system attacks healthy tissues, causing inflammation and damage in various body parts. Participants will be randomly …
This study investigates the effects of an investigational medication on people with moderate to severe ulcerative colitis (UC). Ulcerative colitis is a condition where the lining of the large intestine becomes inflamed and develops sores. The study will compare different doses of the investigational medication to a placebo, which is …
This study investigates the effects of an investigational medication compared to an existing treatment in people with relapsing forms of multiple sclerosis, a condition where the immune system mistakenly attacks the protective covering of the nerves, causing communication problems between the brain and the rest of the body. The study …
This study investigates the efficacy and safety of an investigational medication in delaying disability progression in individuals with non-relapsing secondary progressive multiple sclerosis (nrSPMS). nrSPMS is a stage of multiple sclerosis (MS) where symptoms worsen over time without periods of remission. Participants will be randomly assigned to receive either the …
This study investigates the effects of an investigational medication for people with moderate-to-severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes itchy, inflamed skin. The study focuses on participants aged 12 years and older who have not responded well to previous treatments, including biologic medications or oral …
This study investigates the effects of an investigational medication on adults with non-responsive celiac disease (NRCD) who are on a gluten-free diet. Celiac disease is a condition where eating gluten leads to damage in the small intestine. The study aims to see how the investigational medication affects the small intestine's …
This study investigates an investigational vaccine for acne, a common inflammatory skin condition that affects many people worldwide, especially teenagers and young adults. Acne causes pimples, blackheads, and other skin issues. The purpose of this study is to learn about the safety, effectiveness, and the body's immune response to different …
An investigational medication is what is being studied to see if symptoms improve while taking it. It is not yet approved for general use by regulatory authorities. This study uses an investigational medication called Riliprubart. The investigational medicine is injected in a vein or under the skin, either at the …
