This study investigates the effectiveness of different investigational medications compared to a placebo in improving lung capacity in participants with Interstitial Lung Disease (ILD) secondary to Systemic Sclerosis (SSc). The purpose is to observe changes from the start to the end of the treatment period at Week 52.Participants in the …
This study investigates the safety and effects of an investigational mRNA vaccine for individuals with mild acne. The study will include two groups, a Sentinel Cohort to initially assess safety, and a Main Cohort for broader evaluation.Participants will receive two administrations of the investigational vaccine. The study will consist of …
This study investigates the safety and effectiveness of a one-time injection into the eye for participants with Geographic Atrophy (GA) due to Age-related Macular Degeneration (AMD). Participants will receive a one-time injection directly into the eye. Some participants in the second part of the study may receive a sham injection, …
This study investigates the experiences of adults with relapsed or refractory multiple myeloma. The purpose is to gather data about patients receiving standard care with an investigational medication. Researchers aim to collect various types of data, including quantitative, qualitative, and wearable data, to understand the treatment experience better.Participants will be …
This study investigates the effects of an investigational medication on adults with Immune Thrombocytopenia (ITP) who have not responded to first-line treatments. The purpose of this study is to assess how early immune modulation with the investigational medication can impact the condition in these patients.Participants in this study will receive …
This study investigates the safety and ability of an investigational pneumococcal vaccine to stimulate the body's immune response in children and adolescents aged 2 to 17 years with sickle cell disease. The study compares the investigational vaccine to a licensed pneumococcal vaccine to see how well they work in producing …
This study investigates the experiences of individuals with stage 2 Type 1 diabetes in the United States. The study compares those who have received an infusion with an investigational medication and those who have not.Participants will provide information on their quality of life, diabetes-related anxiety, and how they manage their …
This study investigates the effects of atopic dermatitis (AD) on pregnancy outcomes. This observational study will compare the incidence of adverse pregnancy outcomes, such as miscarriage or stillbirth, and the prevalence of adverse infant outcomes, like major congenital malformations or being small for gestational age, in women with AD who …
This study investigates the effects and outcomes of systemic treatments in patients with atopic dermatitis (AD). The purpose of this study is to understand the patient journey and assess the safety and clinical outcomes of these treatments in a real-world setting. Atopic dermatitis can vary in severity, and systemic treatments …
This study investigates the long-term safety and effectiveness of therapies for non-neoplastic hematologic disorders. The purpose is to collect data from participants with various blood disorders, such as hemophilia, von Willebrand Disease, and congenital platelet disorders, over a period of at least 15 years. Participants will be grouped into specific …
