This study investigates the effects and safety of an investigational medication in adults with Graves' disease. Some participants may also have Graves' orbitopathy, which affects the eyes.Participants in this study will be assigned to one of two study arms, each receiving a different dose of the investigational medication. The study …
This study investigates the efficacy and safety of an investigational medication in people with moderately to severely active Crohn's Disease (CD). The study is divided into three sub-studies to evaluate how well the medication works and how safe it is for participants.Participants in the study may undergo several procedures, including …
This study investigates the efficacy and safety of an investigational medication in individuals with moderately to severely active Crohn's Disease. The study involves a comparison between the investigational medication and a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.Participants will …
This study investigates the effects of an investigational medication compared to a placebo in adults with chronic obstructive pulmonary disease (COPD) that is not well controlled and is characterized by a higher number of eosinophils, a type of white blood cell. The purpose of this study is to assess how …
This study investigates the effects of an investigational medication compared to a placebo in adults with Chronic Obstructive Pulmonary Disease (COPD) that is not well controlled and is characterized by an eosinophilic phenotype. An eosinophilic phenotype refers to a certain type of inflammation in the lungs, which can affect how …
This study investigates the effect of an investigational medication, an Anti-OX40L Monoclonal Antibody, in adults with moderate to severe atopic dermatitis. The study will compare the investigational medication to other treatment arms to assess its effectiveness.Participants will be randomly assigned to one of five study arms in a double-blind manner, …
This study investigates the safety and effectiveness of an investigational medication in participants with chronic graft versus host disease (cGVHD). The study focuses on Black or African American, American Indian or Alaska Native, and Native Hawaiian or Other Pacific Islander participants who have already been treated with at least two …
This study investigates the effects of switching from emicizumab to an investigational medication for individuals with severe hemophilia A. The purpose of this study is to understand the safety and tolerability of the investigational medication after participants transition from their current preventive treatment.Participants will undergo a screening period followed by …
This study investigates the long-term effects of an investigational medication in adults with Alpha-1 Antitrypsin Deficiency (AATD) emphysema. The purpose of this study is to understand how the investigational medication affects individuals with this condition over an extended period.Participants in this study will receive the investigational medication and will be …
This study investigates the use of a subcutaneous investigational medication in combination with carfilzomib and dexamethasone for adults with relapsed or refractory multiple myeloma. The study aims to determine how effective this combination is in treating this condition.Participants in the study will receive the investigational medication through a system that …
