This study investigates a treatment for Crohn's disease, focusing on comparing the effectiveness of different doses of an investigational medication with a placebo in people with moderate to severe Crohn's disease.Participants in this study will be randomly assigned to one of three study arms. They will receive either different doses …
This study investigates the effect of an investigational medication, an Anti-OX40L Monoclonal Antibody, in adults with moderate to severe atopic dermatitis. The study will compare the investigational medication to other treatment arms to assess its effectiveness.Participants will be randomly assigned to one of five study arms in a double-blind manner, …
This study investigates the effects of switching from emicizumab to an investigational medication for individuals with severe hemophilia A. The purpose of this study is to understand the safety and tolerability of the investigational medication after participants transition from their current preventive treatment.Participants will undergo a screening period followed by …
This study investigates the safety, efficacy, and immune response of an investigational mRNA vaccine for adults with moderate to severe acne. This study aims to evaluate how well the vaccine works at different doses in participants aged 18 to 45 years.Participants in the study will receive up to three intramuscular …
This study investigates the long-term effects of an investigational medication in adults with Alpha-1 Antitrypsin Deficiency (AATD) emphysema. The purpose of this study is to understand how the investigational medication affects individuals with this condition over an extended period.Participants in this study will receive the investigational medication and will be …
This study investigates the effectiveness of different investigational medications compared to a placebo in improving lung capacity in participants with Interstitial Lung Disease (ILD) secondary to Systemic Sclerosis (SSc). The purpose is to observe changes from the start to the end of the treatment period at Week 52.Participants in the …
This study investigates the safety and effects of an investigational mRNA vaccine for individuals with mild acne. The study will include two groups, a Sentinel Cohort to initially assess safety, and a Main Cohort for broader evaluation.Participants will receive two administrations of the investigational vaccine. The study will consist of …
This study investigates the experiences of adults with relapsed or refractory multiple myeloma. The purpose is to gather data about patients receiving standard care with an investigational medication. Researchers aim to collect various types of data, including quantitative, qualitative, and wearable data, to understand the treatment experience better.Participants will be …
This study investigates the safety and ability of an investigational pneumococcal vaccine to stimulate the immune system in children and adolescents with sickle cell disease. Participants will receive either the investigational vaccine or a licensed pneumococcal vaccine, and researchers will compare the immune response between the two groups.Participants in the …
This study investigates how a medicine given by shot under the skin compares to being given through a vein for people with Multiple Sclerosis (MS). Participants will be in the study for 48 weeks, which is about 12 months.Participants will either get the medicine through a shot under the skin …
