This study investigates the effects of investigational medications on primary focal segmental glomerulosclerosis (FSGS) and primary minimal change disease (MCD). FSGS and MCD are kidney disorders that cause proteinuria, which is an excess of protein in the urine. The purpose of this study is to see how these investigational medications …
This study investigates the long-term safety and efficacy of an investigational medication in adults with moderate-to-severe asthma. Asthma is a condition where the airways in the lungs swell and narrow, making it hard to breathe. The participants in this study have already completed a previous study and will continue using …
This study investigates the effects of an investigational medication in patients with relapsed or refractory multiple myeloma (RRMM). Multiple myeloma is a type of cancer that affects plasma cells, which are a kind of white blood cell in the bone marrow. The purpose of the study is to find the …
This study investigates the safety and immune response to an investigational vaccine designed to prevent lower respiratory tract disease caused by human metapneumovirus (hMPV) and respiratory syncytial virus (RSV) in adults aged 60 years and older. The study aims to understand how well the vaccine works in creating an immune …
This study investigates the effects of an investigational medication on adults with moderate-to-severe ulcerative colitis (UC). Ulcerative colitis is a long-term condition that causes inflammation and sores in the digestive tract, particularly affecting the lining of the large intestine and rectum. The purpose of this study is to evaluate how …
This study investigates the use of an investigational medication for erectile dysfunction. Erectile dysfunction is when someone has trouble getting or keeping an erection. The study will look at whether participants can properly choose and use the medication by following the instructions on the label and completing a health survey. …
This study investigates the safety and how well the body responds to two different pneumococcal vaccines in infants, toddlers, and children. Pneumococcal vaccines help protect against infections caused by the bacteria Streptococcus pneumoniae, which can lead to illnesses like pneumonia. The study involves comparing an investigational vaccine to an existing …
This study investigates the effects and safety of an investigational medication on individuals with Graves' disease, which is an autoimmune disorder that causes the thyroid gland to produce excessive hormones. Some participants may also have Graves' orbitopathy, a condition where the tissues around the eyes become inflamed. The study involves …
This study investigates the safety and ability of an investigational pneumococcal conjugate vaccine to stimulate the immune system in infants. The study compares this investigational vaccine with a licensed pneumococcal vaccine. Infants aged approximately 2 months will receive these vaccines alongside routine pediatric vaccines to see how well their bodies …
This study investigates the safety of an investigational vaccine compared to a licensed vaccine for yellow fever in adults aged 18 to 60 years. Yellow fever is a viral infection transmitted by mosquitoes, which can cause fever, chills, loss of appetite, nausea, muscle pains, and headaches. The study aims to …
