This study investigates the efficacy and safety of an investigational medication in people with sickle-cell disease.The focus of this study is to evaluate how well the investigational medication works and how safe it is for participants with sickle-cell disease.Who can participate: Participants aged 10 to 65 years with diagnosed sickle-cell …
This study investigates the effects of an investigational medication given once a week to people with Hemophilia A who have joint swelling known as synovial hypertrophy. Participants in this study will receive the investigational medication once a week for about 12 months. During the study, doctors will monitor the participants' …
This study investigates the treatment of Crohn's disease. The purpose of this study is to evaluate the effectiveness and safety of an investigational medication for people with moderate to severe Crohn's disease.The focus of the study is on assessing the effectiveness of different doses of the investigational medication compared to …
This study investigates the treatment of immune thrombocytopenia (ITP) in adults who did not respond to first-line treatments. The purpose is to evaluate the effects of a new investigational medication. Participants will be in the study for a total of 60 weeks. This includes a screening period of up to …
This study investigates chronic graft versus host disease (cGVHD) in children who have undergone a stem cell or bone marrow transplant. The purpose of this study is to understand how the investigational medication works in children with moderate to severe cGVHD. Participants will be in the study for up to …
This study investigates the efficacy and safety of an investigational medication in people with moderately to severely active Crohn's Disease (CD). The purpose of this study is to learn more about how well the investigational medication works and how safe it is for participants with CD.Participants in the study will …
This study investigates the efficacy and safety of an investigational medication in people with moderately to severely active Crohn's Disease.The purpose of this study is to evaluate how well the investigational medication works and how safe it is for people with Crohn's Disease. The study will gather information to understand …
This study investigates advanced solid tumors in adults. Participants in this study have tumors that are either hard to treat or have spread to other parts of the body, making them unresectable or metastatic.The purpose of this study is to evaluate the safety of an investigational medication in treating these …
This study investigates the effectiveness of adding an investigational medication to the treatment regimen of patients with uncontrolled asthma. Uncontrolled asthma refers to patients who continue to experience frequent symptoms despite their current medication. The study compares two treatment arms: one where participants receive the investigational medication along with their …
This study investigates the effect of an investigational medication, an Anti-OX40L Monoclonal Antibody, in adults with moderate to severe atopic dermatitis. The study will compare the investigational medication to other treatment arms to assess its effectiveness.Participants will be randomly assigned to one of five study arms in a double-blind manner, …
