This study investigates the efficacy and safety of an investigational medication in people with moderately to severely active Crohn's Disease.The study focuses on evaluating the safety and effectiveness of the investigational medication over a long period. Researchers aim to understand how the treatment impacts symptoms and overall health.Who can participate: …
This study investigates advanced solid tumors, focusing on how an investigational medication works in treating these tumors, especially when they have become difficult to treat or have spread throughout the body.The study focuses on evaluating the safety of the investigational medication. It aims to determine how well the medication can …
This study investigates the effectiveness of adding an investigational medication to the treatment regimen of patients with uncontrolled asthma. Uncontrolled asthma refers to patients who continue to experience frequent symptoms despite their current medication. The study compares two treatment arms: one where participants receive the investigational medication along with their …
This study investigates the treatment of moderate-to-severe atopic dermatitis (AD) in participants aged 12 years and older. The purpose is to evaluate the effects of a subcutaneous treatment for those who have not responded well to previous biologic therapies or oral JAK inhibitors.The study will focus on assessing the safety …
This study investigates the safety and efficacy of an investigational medication in people with sickle-cell disease (SCD). The focus of the study is to evaluate how well the investigational medication works and how safe it is for participants with SCD. Researchers aim to gather information that could help improve understanding …
This study investigates the use of an investigational medication in children with chronic graft versus host disease (cGVHD). This study focuses on children who have moderate to severe cGVHD that hasn't improved with at least two other treatments.The study aims to understand how the investigational medication affects children with cGVHD. …
This study investigates asthma in adults and aims to evaluate the long-term safety and effectiveness of an investigational medication. The focus of the study is to observe how participants respond to the investigational medication over a longer period. The study aims to gather information about the safety and effectiveness of …
This study investigates the effect of an investigational medication, an Anti-OX40L Monoclonal Antibody, in adults with moderate to severe atopic dermatitis. The study will compare the investigational medication to other treatment arms to assess its effectiveness.Participants will be randomly assigned to one of five study arms in a double-blind manner, …
This study investigates the effects of switching from emicizumab to an investigational medication for individuals with severe hemophilia A. The purpose of this study is to understand the safety and tolerability of the investigational medication after participants transition from their current preventive treatment.Participants will undergo a screening period followed by …
This study investigates the safety, efficacy, and immune response of an investigational mRNA vaccine for adults with moderate to severe acne. This study aims to evaluate how well the vaccine works at different doses in participants aged 18 to 45 years.Participants in the study will receive up to three intramuscular …
