This study investigates the effectiveness and safety of three investigational medications compared to a placebo in treating primary focal segmental glomerulosclerosis (FSGS) or primary minimal change disease (MCD). These kidney disorders can lead to nephrotic syndrome, characterized by high levels of protein in the urine (proteinuria). The purpose of this …
This study investigates the long-term safety and efficacy of an investigational medication in adult participants with asthma. Participants who have completed previous studies with the investigational medication are eligible to join this extended study.Participants will receive the investigational medication and continue their background therapy, which may include inhaled corticosteroids and …
This study investigates the safety and efficacy of an investigational medication injected under the skin in adult participants with relapsed or refractory multiple myeloma. This study aims to determine the best dose of the investigational medication for future research.Participants will be involved in two parts of the study. In Part …
This study investigates the ability of participants to appropriately select and use an investigational medication for erectile dysfunction using specific labeling and a health survey assessment (HSA). The study will enroll men interested in an over-the-counter treatment for this condition.Participants will enter the study through an open-label process, meaning both …
This study investigates the effects of an investigational medication given once a week to people with Hemophilia A who have joint swelling known as synovial hypertrophy. Participants in this study will receive the investigational medication once a week for about 12 months. During the study, doctors will monitor the participants' …
This study investigates the efficacy and safety of an investigational medication in patients with moderate to severe Crohn's disease. The study involves different doses of the investigational medication compared to a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.Participants will …
This study investigates airway inflammation in people aged 40 to 85 with Chronic Obstructive Pulmonary Disease (COPD). The study aims to compare the effects of an investigational medication with a placebo on lung health, including inflammation and mucus buildup, and how these factors relate to lung function and quality of …
This study investigates the use of an investigational medication in children with chronic Graft Versus Host Disease (cGVHD). The purpose of this study is to understand how the investigational medication is processed in the body and to determine the appropriate dose for children aged 1 to less than 18 years …
This study investigates the efficacy and safety of an investigational medication in people with moderately to severely active Crohn's Disease (CD). The study is divided into three sub-studies to evaluate how well the medication works and how safe it is for participants.Participants in the study may undergo several procedures, including …
This study investigates the efficacy and safety of an investigational medication in individuals with moderately to severely active Crohn's Disease. The study involves a comparison between the investigational medication and a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.Participants will …
