This study investigates nonrelapsing secondary progressive multiple sclerosis (nrSPMS). The purpose of this study is to see how well an investigational medication works in slowing down the progression of disability in people with nrSPMS.Participants will be randomly assigned to receive either the investigational medication or a placebo, which is an …
This study investigates the effects of an investigational medication on children aged 2 to less than 6 years with uncontrolled asthma or severe asthmatic wheeze. The purpose is to understand how this medication can affect these young patients who have difficulty managing their asthma symptoms.The study focuses on evaluating the …
This study investigates the effectiveness and safety of an investigational treatment for people aged 12 and older with moderate-to-severe atopic dermatitis (AD). Participants must have had an inadequate response to previous biologic therapy or an oral JAK inhibitor. The study involves using a subcutaneous solution alongside topical corticosteroids.The purpose is …
This study investigates the treatment of primary focal segmental glomerulosclerosis (FSGS) and primary minimal change disease (MCD) in participants aged 16 to 75 years. These conditions affect the kidneys and can lead to nephrotic syndrome, which is characterized by high levels of protein in the urine.The focus of the study …
This study investigates the long-term safety and effectiveness of an investigational medication in adults with asthma.The focus of this study is to observe how well the investigational medication works over an extended period and to monitor any side effects that may occur. The study aims to provide more information about …
This study investigates the safety and effectiveness of an investigational medication for adults with relapsed or refractory myeloma. The research aims to understand how well the medication works and how safe it is for people who have tried other treatments without success.The study focuses on evaluating the investigational medication's effects …
This study investigates the ability of participants to appropriately select and use an investigational medication for erectile dysfunction using specific labeling and a health survey assessment (HSA). The study will enroll men interested in an over-the-counter treatment for this condition.Participants will enter the study through an open-label process, meaning both …
This study investigates the safety and efficacy of an investigational gene therapy for individuals with non-congenital myotonic dystrophy type 1 (DM1). The purpose of this study is to assess how well the investigational therapy can reduce levels of a specific protein linked to DM1 and improve muscle function in participants …
This study investigates the safety and effectiveness of an investigational medication for individuals with sickle-cell disease. The study aims to evaluate how well the investigational medication works and its safety for people with sickle-cell disease. It focuses on understanding the medication's effects on the condition.Who can participate: Participants aged 10 …
This study investigates the effects of an investigational medication given once a week to people with Hemophilia A who have joint swelling known as synovial hypertrophy. Participants in this study will receive the investigational medication once a week for about 12 months. During the study, doctors will monitor the participants' …
