This study investigates the safety of an investigational pneumococcal vaccine compared to a licensed vaccine in infants. The purpose is to understand how the investigational vaccine performs in young children aged 2 to 3 months. Pneumococcal vaccines are used to protect against infections caused by the bacterium Streptococcus pneumoniae, which …
This study investigates the safety and immune response of an investigational pneumococcal conjugate vaccine in infants. Pneumococcal vaccines are designed to protect against infections caused by the bacteria Streptococcus pneumoniae. The study aims to determine how well the investigational vaccine works in creating antibodies, which are proteins that help fight …
This study investigates the effects of an investigational medication for people with chronic rhinosinusitis with nasal polyps (CRSwNP). CRSwNP is a condition where the tissue inside the nose becomes swollen and forms small growths called polyps. The study compares two different doses of the investigational medication to a placebo, which …
This study investigates the effects of an investigational medication on people with chronic rhinosinusitis with nasal polyps (CRSwNP). CRSwNP is a condition where the lining of the nasal passages and sinuses becomes swollen, leading to the growth of polyps. The study will compare two different dosing regimens of the investigational …
This study investigates the use of an investigational medication for children and adolescents with prurigo nodularis, a skin condition characterized by itchy nodules. The purpose of the study is to assess the safety and how the body processes the medication in participants aged 6 months to less than 18 years.Participants …
This study investigates the interactions between type 2 diabetes (T2DM) and periodontitis (PD), which is a serious gum infection that can damage gums and destroy the jawbone. The purpose is to understand how these two conditions affect each other. Participants will be divided into nine different study arms based on …
This study investigates the safety and effects of an investigational medication given as a one-time injection into one eye for people with neovascular age-related macular degeneration (nAMD). Neovascular age-related macular degeneration is a condition where abnormal blood vessels grow under the retina, leading to vision loss. The study is conducted …
This study investigates the long-term safety, tolerability, and efficacy of an investigational medication in adults with chronic rhinosinusitis with nasal polyps (CRSwNP) who have completed a previous clinical study with the same medication. CRSwNP is a condition where growths called polyps form in the nasal passages and sinuses, leading to …
This study investigates chronic inflammatory demyelinating polyneuropathy (CIDP), a condition where the body's immune system attacks the protective covering of the nerves, leading to muscle weakness and numbness. The purpose of this study is to observe individuals in the United States who have been diagnosed with CIDP and continue to …
The purpose of this study is to investigate the effectiveness of different doses of an investigational medication compared to a placebo in treating moderate to severe Ulcerative Colitis. Ulcerative Colitis is a long-term condition that causes inflammation and ulcers in the digestive tract, primarily affecting the innermost lining of the …