This study investigates the effects of an investigational medication for people with chronic rhinosinusitis with nasal polyps (CRSwNP). CRSwNP is a condition where the tissue inside the nose becomes swollen and forms small growths called polyps. The study compares two different doses of the investigational medication to a placebo, which …
This study investigates the effects of an investigational medication on people with chronic rhinosinusitis with nasal polyps (CRSwNP). CRSwNP is a condition where the lining of the nasal passages and sinuses becomes swollen, leading to the growth of polyps. The study will compare two different dosing regimens of the investigational …
This study investigates the use of an investigational medication for children and adolescents with prurigo nodularis, a skin condition characterized by itchy nodules. The purpose of the study is to assess the safety and how the body processes the medication in participants aged 6 months to less than 18 years.Participants …
This study investigates the effects of an investigational medication given with other treatments to adults with relapsed or refractory multiple myeloma (RRMM). Multiple myeloma is a cancer of the plasma cells in the bone marrow. The purpose of this study is to assess how well the investigational medication works when …
This study investigates the interactions between type 2 diabetes (T2DM) and periodontitis (PD), which is a serious gum infection that can damage gums and destroy the jawbone. The purpose is to understand how these two conditions affect each other. Participants will be divided into nine different study arms based on …
This study investigates the safety and effects of an investigational medication given as a one-time injection into one eye for people with neovascular age-related macular degeneration (nAMD). Neovascular age-related macular degeneration is a condition where abnormal blood vessels grow under the retina, leading to vision loss. The study is conducted …
This study investigates the safety and immune response of a second-generation investigational vaccine for H5 influenza, a type of flu virus. The study includes healthy younger and older adults to determine the best dose for future research. The investigational vaccine uses a technology called mRNA, which helps the body recognize …
This study investigates the use of an investigational medication in combination with other agents to treat individuals with relapsed or refractory myeloma. Myeloma is a type of cancer that affects plasma cells in the bone marrow, leading to issues such as bone pain, anemia, and infections. The study includes multiple …
This study investigates the effect of an investigational medication compared to standard care in preventing or slowing the decline of lung function in adults with uncontrolled moderate to severe asthma. Asthma is a condition where the airways in the lungs become inflamed and narrow, making it hard to breathe. The …
This study investigates the safety and effects of an investigational medication in people with blood cancers such as acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). These are conditions where the blood and bone marrow make abnormal blood cells. The study aims to understand how the body processes the medication …
