This study investigates the safety and effectiveness of a one-time intravitreal dose of an investigational medication in adults with neovascular age-related macular degeneration (nAMD). The study is conducted in two parts: Part I involves evaluating different dose levels in successive groups of participants, while Part II involves randomizing participants to …
This study investigates the pharmacokinetics and safety of an investigational medication in children aged 6 months to under 18 years with prurigo nodularis. The purpose of the study is to understand how the investigational medication is processed in the body and to assess its safety for the participants.Participants in the …
This study investigates the effects of a single oral dose of an investigational medication on cardiac repolarization in healthy adults. The study is a Phase 1 trial, meaning it is an early stage of testing, and involves several different treatment arms to compare the investigational medication with a placebo and …
This study investigates the effects of an investigational medication in children who have eosinophilic esophagitis. The purpose of this study is to understand how this condition impacts young children.The study focuses on evaluating the safety, tolerability, and effectiveness of the investigational medication over a period of time. Researchers are also …
This study investigates chronic inflammatory demyelinating polyneuropathy (CIDP), focusing on individuals with residual impairment or disability after receiving standard treatments for at least three months. The purpose of this observational study is to collect data on people with CIDP to better understand how treatments work in real-world settings.Participants will continue …
This study investigates the outcomes for mothers and their babies when the mothers receive the investigational vaccine during pregnancy. The focus is on understanding how the vaccine affects maternal health, pregnancy progress, and the newborn's health. Outcomes will be closely monitored to gather important data on these aspects.Participants in the …
This study investigates eosinophilic esophagitis (EoE) in patients who have been prescribed an investigational medication as part of their standard care. The purpose is to understand the experiences of these patients and how the condition affects them.The study focuses on observing how the investigational medication is used in routine care …
This study investigates the use of an investigational medication in combination with other novel agents in participants with relapsed or refractory multiple myeloma (RRMM). The study includes several substudies with different combinations of treatments, some with and some without the drug dexamethasone.Participants in this study will undergo various procedures depending …
This study investigates the ability of participants to appropriately select and use an investigational medication for erectile dysfunction using specific labeling and a health survey assessment (HSA). The study will enroll men interested in an over-the-counter treatment for this condition.Participants will enter the study through an open-label process, meaning both …
This study investigates the effects of an investigational medication given once a week to people with Hemophilia A who have joint swelling known as synovial hypertrophy. Participants in this study will receive the investigational medication once a week for about 12 months. During the study, doctors will monitor the participants' …
