This study investigates the effects of an investigational medication compared to a placebo in adults and adolescents with newly diagnosed Type 1 diabetes (T1D) who are already on insulin therapy. Participants will be randomly assigned to receive one of three different doses of the investigational medication or a placebo, which …
This study investigates the effectiveness and safety of an investigational medication compared to a placebo in individuals aged 1 to 25 years with Stage 3 Type 1 diabetes. Participants in this study will have recently been diagnosed with Stage 3 Type 1 diabetes and are already on standard insulin therapy.Participants …
This study investigates the effectiveness and safety of an investigational medication compared to a placebo in treating chronic lung allograft dysfunction (CLAD) in adults who have had a lung transplant. Participants in this study must have had their transplant at least a year ago and must be experiencing progression of …
This study investigates the improvement of itching in individuals with Lichen Simplex Chronicus (LSC) using subcutaneous injections of an investigational medication compared to placebo. The study involves male and female participants who are 18 years or older and have moderate-to-severe LSC.Participants in the study will receive either the investigational medication …
This study investigates the effect of an investigational medication on reducing itchiness in individuals with Lichen Simplex Chronicus (LSC). The purpose of this study is to compare the effectiveness of the investigational medication given by injection to a placebo in adults aged 18 and over who have moderate-to-severe LSC.Participants will …
This study investigates the safety and ability of an investigational pneumococcal conjugate vaccine to stimulate the immune system in healthy infants. Infants between 42 and 89 days old will receive either the investigational vaccine or a licensed pneumococcal vaccine, alongside routine pediatric vaccines. The purpose is to compare the immune …
This study investigates the safety of an investigational pneumococcal vaccine in healthy infants aged approximately 2 months. The purpose is to compare its safety profile to a licensed 20-valent pneumococcal conjugate vaccine. Infants participating in the study will receive either the investigational vaccine or the licensed vaccine as part of …
This study investigates the safety and immune response of an investigational pneumococcal conjugate vaccine, referred to as PCV21, in infants. The purpose is to determine if PCV21 can stimulate the production of antibodies when administered after one, two, or three doses of a licensed 20-valent pneumococcal vaccine. This is compared …
This study investigates the effects of an investigational medication in people with chronic rhinosinusitis with nasal polyps (CRSwNP). The purpose of this study is to evaluate how well the investigational medication works, how safe it is, and how well people tolerate it when added to standard treatment with intranasal corticosteroids.Participants …
This study investigates the effects of an investigational medication on individuals with chronic rhinosinusitis with nasal polyps (CRSwNP). The purpose of this study is to assess the efficacy, safety, and tolerability of two dosing regimens of the investigational medication compared to a placebo, alongside intranasal corticosteroids (INCS).Participants will be randomly …
