This study investigates the efficacy and safety of an investigational medication in delaying disability progression in individuals with non-relapsing secondary progressive multiple sclerosis (nrSPMS). nrSPMS is a stage of multiple sclerosis (MS) where symptoms worsen over time without periods of remission. Participants will be randomly assigned to receive either the …
This study investigates the effects of an investigational medication for people with moderate-to-severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes itchy, inflamed skin. The study focuses on participants aged 12 years and older who have not responded well to previous treatments, including biologic medications or oral …
This study investigates the effect of an investigational medication compared to a placebo in people with recently diagnosed Type 1 diabetes who are on insulin therapy. Type 1 diabetes is a chronic disease where the body's defense system mistakenly attacks specific cells within the pancreas, which make insulin. Insulin helps …
This study investigates the efficacy and safety of an investigational medication compared to a placebo in individuals aged 1 to 25 years with Stage 3 Type 1 diabetes. Type 1 diabetes is a chronic disease where the body's defense system mistakenly attacks specific cells within the pancreas, which make insulin. …
This study investigates the efficacy and safety of an investigational medication compared to a placebo in patients who have undergone a bilateral lung transplant and have chronic lung allograft dysfunction (CLAD). CLAD is a condition where the lung function declines over time after a transplant. Participants must be at least …
This study investigates the effects of an investigational medication on pruritus, which is a severe itching sensation, in individuals with Lichen Simplex Chronicus (LSC). LSC is a skin condition characterized by thickened, itchy patches of skin. The study compares the investigational medication given through subcutaneous injections to placebo injections in …
This study investigates the effectiveness of an investigational medication compared to a placebo in treating pruritus, or severe itching, in adults with Lichen Simplex Chronicus (LSC). LSC is a skin condition characterized by thickened, itchy patches of skin. The purpose of this study is to see if the investigational medication …
This study investigates the safety and ability of an investigational pneumococcal vaccine to stimulate the body's defense system in infants. The study compares this investigational vaccine with a licensed pneumococcal vaccine when given alongside routine vaccines to infants aged about 2 months. The investigational vaccine is being tested to see …
This study investigates the safety of an investigational pneumococcal vaccine compared to a licensed vaccine in infants. The purpose is to understand how the investigational vaccine performs in young children aged 2 to 3 months. Pneumococcal vaccines are used to protect against infections caused by the bacterium Streptococcus pneumoniae, which …
This study investigates the safety and immune response of an investigational pneumococcal conjugate vaccine in infants. Pneumococcal vaccines are designed to protect against infections caused by the bacteria Streptococcus pneumoniae. The study aims to determine how well the investigational vaccine works in creating antibodies, which are proteins that help fight …
