This study investigates the efficacy and safety of an investigational medication compared to a placebo in participants aged 1 to 25 years with Stage 3 Type 1 diabetes. Participants will be randomly assigned to receive either the investigational medication or a placebo, both administered by intravenous infusion.Participants will undergo various …
This study investigates the safety and ability of an investigational pneumococcal conjugate vaccine to stimulate the immune system in healthy infants. Infants between 42 and 89 days old will receive either the investigational vaccine or a licensed pneumococcal vaccine, alongside routine pediatric vaccines. The purpose is to compare the immune …
This study investigates the safety of an investigational pneumococcal vaccine in healthy infants aged approximately 2 months. The purpose is to compare its safety profile to a licensed 20-valent pneumococcal conjugate vaccine. Infants participating in the study will receive either the investigational vaccine or the licensed vaccine as part of …
This study investigates the long-term safety, tolerability, and effectiveness of an investigational medication in adults with chronic rhinosinusitis with nasal polyps (CRSwNP). Participants in this study have previously completed a related clinical study.Participants will receive the investigational medication and will continue using an intranasal spray as part of the study …
This study investigates the efficacy, safety, and tolerability of an investigational medication in adults with chronic rhinosinusitis with nasal polyps (CRSwNP). The study includes participants aged 18 and older who have not had success with standard treatments.Participants will receive either the investigational medication or a placebo, in addition to their …
This study investigates the effectiveness and safety of an investigational medication in treating adults with moderate to severe Ulcerative Colitis. The study will compare different doses of the investigational medication to a placebo to see which works best.Participants will be randomly assigned to one of three study arms. They will …
This study investigates an investigational medication for individuals with moderate to severe hidradenitis suppurativa. The purpose of this study is to understand how different doses of the investigational medication affect people with this condition.Participants in the study will be randomly assigned to receive either the investigational medication or a placebo, …
This study investigates the safety and immune response of an investigational pneumococcal conjugate vaccine (PCV21) in healthy infants. The purpose is to compare the antibody production when PCV21 is administered after 1, 2, or 3 doses of a licensed 20-valent pneumococcal vaccine, versus a complete series of the 20-valent vaccine …
This study investigates the effectiveness and safety of an investigational medication compared to a placebo for adult participants with chronic lung allograft dysfunction (CLAD). Participants in this study must have had a bilateral lung transplant at least one year prior and must be experiencing progressive CLAD despite being on azithromycin …
This study investigates the efficacy, safety, and tolerability of an investigational medication in participants with chronic rhinosinusitis with nasal polyps (CRSwNP). The study aims to compare two dosing regimens of the investigational medication with a placebo, in addition to standard treatment with intranasal corticosteroids.Participants will undergo a series of procedures …
