This study investigates the effects of an investigational medication in adults with non-responsive celiac disease (NRCD) who follow a gluten-free diet. This study aims to understand how the investigational medication affects intestinal damage caused by gluten exposure, as measured by the villous height to crypt depth ratio, and its impact …
This study investigates the safety and ability of an investigational pneumococcal conjugate vaccine to stimulate the immune system in healthy infants. Infants between 42 and 89 days old will receive either the investigational vaccine or a licensed pneumococcal vaccine, alongside routine pediatric vaccines. The purpose is to compare the immune …
This study investigates the safety of an investigational pneumococcal vaccine in healthy infants aged approximately 2 months. The purpose is to compare its safety profile to a licensed 20-valent pneumococcal conjugate vaccine. Infants participating in the study will receive either the investigational vaccine or the licensed vaccine as part of …
This study investigates the safety and immune response of an investigational pneumococcal conjugate vaccine, referred to as PCV21, in infants. The purpose is to determine if PCV21 can stimulate the production of antibodies when administered after one, two, or three doses of a licensed 20-valent pneumococcal vaccine. This is compared …
This study investigates the safety and effects of an investigational mRNA vaccine for individuals with mild acne. The study will include two groups, a Sentinel Cohort to initially assess safety, and a Main Cohort for broader evaluation.Participants will receive two administrations of the investigational vaccine. The study will consist of …
This study investigates the use of electronic health record (EHR) data from the TriNetX network to support chlamydia research. The purpose is to validate the use of diagnostic codes for identifying chlamydia infections and to describe testing and treatment patterns in the United States.Participants' medical records will be analyzed to …
