These clinical studies are investigating the safety and efficacy of an investigational medication for patients with moderate to severe COPD and who are either current smokers or have a history of smoking.
This study investigates the effectiveness and safety of an investigational medication compared to a placebo for treating chronic lung allograft dysfunction (CLAD) in adults. Participants will have already undergone a bilateral lung transplant and will be receiving a standard treatment regimen including azithromycin and immunosuppression therapies.Participants in the study will …
This study investigates the effect of an investigational medication on airway inflammation in people with Chronic Obstructive Pulmonary Disease (COPD). Participants will be in the study for up to 40 weeks. During this time, the effects on airway resistance and remodeling, including mucus plugging, will be assessed to see if …
This study investigates advanced solid tumors, focusing on the safety of an investigational medication, a type of antibody-drug conjugate (ADC), in participants with these challenging-to-treat cancers.Participants will take part in a study with five different parts. Parts A and B will focus on determining the appropriate dosage of the investigational …
This study investigates the effectiveness of different investigational medications compared to a placebo in improving lung capacity in participants with Interstitial Lung Disease (ILD) secondary to Systemic Sclerosis (SSc). The purpose is to observe changes from the start to the end of the treatment period at Week 52.Participants in the …
This study investigates the long-term effects of an investigational medication in adults with Alpha-1 Antitrypsin Deficiency (AATD) emphysema. The purpose of this study is to understand how the investigational medication affects individuals with this condition over an extended period.Participants in this study will receive the investigational medication and will be …
