This study investigates the safety and immune response of a high-dose influenza vaccine combined with a recombinant COVID-19 vaccine in adults aged 50 years and older. The study will compare the effects of different doses of the investigational vaccines given together to those given separately. Participants will receive injections in …
This study investigates the use of an investigational medication for erectile dysfunction in men. Erectile dysfunction is when a man has trouble getting or keeping an erection. The purpose of this study is to see if men can follow instructions and use the medication correctly by reading the label and …
This study investigates the use of an investigational medication in adults with moderate to severe Crohn's Disease (CD). Crohn's Disease is a long-lasting condition that causes inflammation in the digestive tract, leading to symptoms like stomach pain and diarrhea. The purpose of this study is to compare the effects of …
This study investigates the use of an investigational medication in adults with non-responsive celiac disease (NRCD) who are following a gluten-free diet. Non-responsive celiac disease is a condition where symptoms persist despite adhering to a gluten-free diet. The purpose of this study is to evaluate the effectiveness of the investigational …
This study investigates the use of an investigational medication to treat adults with moderate to severe atopic dermatitis, a skin condition that causes itchy and inflamed skin. Atopic dermatitis is a chronic condition that can significantly affect a person's quality of life. The purpose of this study is to evaluate …
This study investigates the effect of an investigational medication on the body's response to vaccines in adults with moderate-to-severe atopic dermatitis, a skin condition that causes itchy and inflamed skin. The purpose of this study is to compare how well the immune system responds to two vaccines: one for tetanus, …
This study investigates the safety and effectiveness of an investigational medication in treating chronic graft-versus-host disease (cGVHD) in Black or African American, American Indian or Alaska Native, and Native Hawaiian or Other Pacific Islander participants. cGVHD is a condition that can occur after a stem cell or bone marrow transplant …
This study investigates how an investigational medication affects the skin barrier in children with moderate-to-severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes red, itchy, and inflamed skin. The study will measure the skin's ability to retain moisture by using a test called transepidermal water loss (TEWL) …
This study investigates the effects of an investigational vaccine for acne, a common skin condition that causes pimples. Acne is one of the most widespread skin issues, affecting millions of people globally. This study will look at how safe and effective the vaccine is for adults aged 18 to 45 …
This study investigates the safety and effects of an investigational medication when combined with other agents in adolescents and adults with blood cancers that express CD123, a protein found on certain cancer cells. The study is divided into different parts to find the best dose and to test how well …
