This study investigates the safety and tolerability of an investigational medication for individuals with Chronic Obstructive Pulmonary Disease (COPD). COPD is a lung condition that makes it hard to breathe. The study includes participants who have completed previous clinical trials and aims to provide additional information on how the treatment …
This study investigates the safety and effectiveness of an investigational medication in children aged 2 to under 6 years with uncontrolled asthma or frequent severe wheezing. Asthma is a condition where the airways in the lungs become narrow and swollen, leading to breathing difficulties. Wheezing is a high-pitched whistling sound …
This study investigates the effects of an investigational medication on esophageal function and remodeling in adults with eosinophilic esophagitis (EoE). EoE is a condition where a type of white blood cell, called eosinophils, builds up in the esophagus, causing inflammation and difficulty swallowing. The purpose of this study is to …
This study investigates the use of an investigational medication for treating moderate-to-severe atopic dermatitis (AD), a skin condition that causes itchy and inflamed skin. The study is designed for participants who have not responded well to previous treatments, including biologic therapies or oral medications known as JAK inhibitors, while using …
This study investigates the long-term safety and tolerability of an investigational medication in adults with different types of multiple sclerosis (MS), including relapsing MS (RMS), primary progressive MS (PPMS), and non-relapsing secondary progressive MS (NRSPMS). MS is a disease where the immune system attacks the protective covering of nerves, which …
This study investigates the maintenance of treatment response in people with moderate-to-severe atopic dermatitis, a skin condition that causes red, itchy, and inflamed skin. The study will compare participants who continue with their initial dose of an investigational medication to those who switch to a different dose or stop treatment.Participants …
This study investigates treatments for primary focal segmental glomerulosclerosis (FSGS) and primary minimal change disease (MCD). FSGS and MCD are kidney conditions that affect how well the kidneys filter waste. The purpose of this study is to see how different treatments affect protein levels in the urine and remission rates …
This study investigates the long-term safety and efficacy of an investigational medication in adults with moderate-to-severe asthma. Asthma is a condition where the airways in the lungs become narrow and swollen, causing breathing difficulties. Participants in this study have previously completed a related study and will continue their treatment in …
This study investigates the safety and immune response of an investigational vaccine designed to prevent lower respiratory tract diseases caused by human metapneumovirus (hMPV) and respiratory syncytial virus (RSV) in adults aged 60 years and older. Lower respiratory tract diseases affect the lungs and can cause serious health issues, especially …
This study investigates the safety and immune response of a recombinant influenza vaccine combined with an adjuvanted recombinant COVID-19 vaccine in adults aged 50 years and older. The study compares different combinations of these vaccines, including the influenza vaccine alone, the COVID-19 vaccine alone, and both vaccines given together in …
