This study investigates the use of an investigational medication in combination with other novel agents in participants with relapsed or refractory multiple myeloma (RRMM). The study includes several substudies with different combinations of treatments, some with and some without the drug dexamethasone.Participants in this study will undergo various procedures depending …
This study investigates the effectiveness and safety of an investigational medication for adults with chronic pruritus of unknown origin (CPUO). Participants in this study will be randomly assigned to one of two study arms, receiving either the investigational medication or a placebo, in addition to their usual treatment with a …
This study investigates an investigational medication for adults with moderate to severe ulcerative colitis (UC). The purpose of this study is to evaluate the effectiveness and safety of the investigational medication compared to a placebo. Participants will be divided into four study arms, with three different doses of the investigational …
This study investigates an investigational medication in adults with advanced solid tumors that cannot be surgically removed or have spread to other parts of the body. The purpose of this study is to assess the safety and initial effectiveness of the investigational medication when used alone or in combination with …
This study investigates the safety and efficacy of an investigational medication for individuals aged 12 and older with moderate to severe atopic dermatitis. The study aims to understand how this medication affects participants over a long-term period.Participants will receive the investigational medication through injections under the skin. This open-label study …
This study investigates the efficacy and safety of an investigational medication in adults with nonrelapsing secondary progressive multiple sclerosis (nrSPMS). The purpose of this study is to determine whether the investigational medication can delay disability progression compared to a placebo.Participants in this randomized, double-blind, placebo-controlled study will receive either the …
This study investigates the effectiveness and safety of three investigational medications compared to a placebo in treating primary focal segmental glomerulosclerosis (FSGS) or primary minimal change disease (MCD). These kidney disorders can lead to nephrotic syndrome, characterized by high levels of protein in the urine (proteinuria). The purpose of this …
This study investigates the safety and efficacy of an investigational medication injected under the skin in adult participants with relapsed or refractory multiple myeloma. This study aims to determine the best dose of the investigational medication for future research.Participants will be involved in two parts of the study. In Part …
This study investigates the ability of participants to appropriately select and use an investigational medication for erectile dysfunction using specific labeling and a health survey assessment (HSA). The study will enroll men interested in an over-the-counter treatment for this condition.Participants will enter the study through an open-label process, meaning both …
This study investigates the effects of an investigational medication given once a week to people with Hemophilia A who have joint swelling known as synovial hypertrophy. Participants in this study will receive the investigational medication once a week for about 12 months. During the study, doctors will monitor the participants' …
