This study investigates the use of an investigational medication for children and adolescents with prurigo nodularis, a skin condition characterized by itchy nodules. The purpose of the study is to assess the safety and how the body processes the medication in participants aged 6 months to less than 18 years.Participants …
This study investigates the interactions between type 2 diabetes (T2DM) and periodontitis (PD), which is a serious gum infection that can damage gums and destroy the jawbone. The purpose is to understand how these two conditions affect each other. Participants will be divided into nine different study arms based on …
This study investigates the safety and effects of an investigational medication given as a one-time injection into one eye for people with neovascular age-related macular degeneration (nAMD). Neovascular age-related macular degeneration is a condition where abnormal blood vessels grow under the retina, leading to vision loss. The study is conducted …
This study investigates the long-term safety, tolerability, and efficacy of an investigational medication in adults with chronic rhinosinusitis with nasal polyps (CRSwNP) who have completed a previous clinical study with the same medication. CRSwNP is a condition where growths called polyps form in the nasal passages and sinuses, leading to …
This study investigates the use of an investigational medication in combination with other agents to treat individuals with relapsed or refractory myeloma. Myeloma is a type of cancer that affects plasma cells in the bone marrow, leading to issues such as bone pain, anemia, and infections. The study includes multiple …
This study investigates the effect of an investigational medication compared to standard care in preventing or slowing the decline of lung function in adults with uncontrolled moderate to severe asthma. Asthma is a condition where the airways in the lungs become inflamed and narrow, making it hard to breathe. The …
This study investigates the safety and effects of an investigational medication in people with blood cancers such as acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). These are conditions where the blood and bone marrow make abnormal blood cells. The study aims to understand how the body processes the medication …
This study investigates the effectiveness and safety of an investigational medication in treating adults with Chronic Pruritus of Unknown Origin (CPUO). Pruritus is a medical term for severe itching. The study includes two parts, Study A and Study B, involving male and female participants aged 18 to 90 years. Participants …
This study investigates a treatment for people with moderately to severely active Ulcerative Colitis (UC) who have an eosinophilic phenotype. Ulcerative Colitis is a condition where the colon and rectum become inflamed. The study aims to evaluate the safety and effectiveness of an investigational medication compared to a placebo. A …
This study investigates the safety and effectiveness of an investigational medication in people with moderate to severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes red, itchy, and inflamed skin. Participants in this study have previously been treated with the investigational medication in earlier trials. The study …
