This study investigates the effects of an investigational medication on individuals with chronic graft versus host disease (cGVHD), a condition where the body's immune system attacks its own tissues after a stem cell or bone marrow transplant. The purpose of this study is to determine if adding the investigational medication …
This study investigates an investigational medication to see if it can improve breathing and symptoms of asthma while reducing future asthma attacks. Asthma is a condition that affects the airways in the lungs, causing them to become narrow and inflamed, which makes it difficult to breathe. The investigational medication is …
This study investigates the efficacy and safety of an investigational medication compared to a placebo in patients who have undergone a bilateral lung transplant and have chronic lung allograft dysfunction (CLAD). CLAD is a condition where the lung function declines over time after a transplant. Participants must be at least …
This study investigates a treatment for chronic rhinosinusitis with nasal polyps (CRSwNP), a condition where growths called polyps form in the nasal passages and sinuses, causing congestion and other symptoms. The purpose of this study is to evaluate the effectiveness and safety of an investigational medication given as an injection …
This study investigates the effects of an investigational medication on pruritus, which is a severe itching sensation, in individuals with Lichen Simplex Chronicus (LSC). LSC is a skin condition characterized by thickened, itchy patches of skin. The study compares the investigational medication given through subcutaneous injections to placebo injections in …
This study investigates the effectiveness of an investigational medication compared to a placebo in treating pruritus, or severe itching, in adults with Lichen Simplex Chronicus (LSC). LSC is a skin condition characterized by thickened, itchy patches of skin. The purpose of this study is to see if the investigational medication …
This study investigates the safety and ability of an investigational pneumococcal vaccine to stimulate the body's defense system in infants. The study compares this investigational vaccine with a licensed pneumococcal vaccine when given alongside routine vaccines to infants aged about 2 months. The investigational vaccine is being tested to see …
This study investigates the safety of an investigational pneumococcal vaccine compared to a licensed vaccine in infants. The purpose is to understand how the investigational vaccine performs in young children aged 2 to 3 months. Pneumococcal vaccines are used to protect against infections caused by the bacterium Streptococcus pneumoniae, which …
This study investigates the safety and immune response of an investigational pneumococcal conjugate vaccine in infants. Pneumococcal vaccines are designed to protect against infections caused by the bacteria Streptococcus pneumoniae. The study aims to determine how well the investigational vaccine works in creating antibodies, which are proteins that help fight …
This study investigates the effects of an investigational medication for people with chronic rhinosinusitis with nasal polyps (CRSwNP). CRSwNP is a condition where the tissue inside the nose becomes swollen and forms small growths called polyps. The study compares two different doses of the investigational medication to a placebo, which …