This study investigates the effects of an investigational medication on individuals with Non-Cystic Fibrosis Bronchiectasis (NCFB). NCFB is a lung condition characterized by persistent cough, chronic sputum production, and frequent respiratory infections. The study aims to evaluate the safety, efficacy, and tolerability of two different dosing regimens of the investigational …
This study investigates an investigational medication for individuals with asthma. Asthma is a condition where the airways in the lungs become inflamed and narrow, making it difficult to breathe. The purpose of this study is to see if the investigational medication can improve breathing and reduce asthma symptoms when used …
This study investigates the effects of an investigational medication given as subcutaneous injections for adults with severe alopecia areata (AA). Alopecia areata is a condition where people lose hair from some or all areas of the body, often from the scalp. The study will compare the investigational medication to a …
This study investigates chronic graft versus host disease (cGVHD), a condition where transplanted donor cells attack the recipient's body after a stem cell or bone marrow transplant. This immune-mediated disorder affects many organs and can lead to inflammation and scarring of tissues. Participants will receive either a corticosteroid with the …
This study investigates the effects of an investigational medication compared to a placebo in adults with moderate to severe hidradenitis suppurativa (HS). HS is a skin condition that causes painful lumps under the skin, often in areas where skin rubs together. The study includes participants aged 18 to 70 years …
This study investigates the RSV vaccine in infants and toddlers. RSV, or Respiratory Syncytial Virus, is a common virus that causes infections in the lungs and respiratory tract. The purpose of this study is to compare the immune response of the RSV vaccine when given alongside routine vaccines at 6 …
This study investigates the effectiveness and safety of an investigational vaccine for Respiratory Syncytial Virus (RSV) in young children. RSV is a virus that causes respiratory infections, which can be serious in infants and young children. The purpose of this study is to compare the investigational vaccine given through the …
This study investigates the effects of an investigational medication combined with other treatments for people with relapsed or refractory myeloma. Myeloma is a type of cancer that affects plasma cells in the bone marrow. The study includes several substudies, each testing different combinations of treatments to see how well they …
This study investigates the use of an investigational medication for patients undergoing kidney transplants. It focuses on two groups: Cohort A, which includes patients with chronic kidney disease who will receive a kidney transplant and may need desensitization, and Cohort B, which includes kidney transplant recipients diagnosed with active antibody-mediated …
This study investigates the treatment of moderate-to-severe rheumatoid arthritis (RA) in adults who have not responded adequately to methotrexate (MTX). Rheumatoid arthritis is a condition where the immune system attacks the joints, causing pain and swelling. Participants will receive either the investigational medication or a placebo, in addition to their …
