This study investigates a gene therapy approach for treating phenylketonuria (PKU), a condition where the body cannot break down an amino acid called phenylalanine (Phe). This happens due to a deficiency in an enzyme called phenylalanine hydroxylase (PAH). The study uses an investigational medication delivered through a virus vector to …
This study investigates the treatment of Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) using an investigational medication. CRSwNP is a condition where polyps, which are small growths, form in the nasal passages and cause blockage and other symptoms. The study includes adults aged 18 to 70 who have not had success …
This study investigates the effects of an investigational medication on people with moderate to severe ulcerative colitis (UC). Ulcerative colitis is a condition that causes inflammation and sores in the lining of the large intestine. The study aims to compare the investigational medication with a placebo, which is an inactive …
This study investigates the rate of relapses in individuals with relapsing forms of multiple sclerosis. Multiple sclerosis (MS) is a condition where the immune system attacks the protective covering of nerves, leading to communication problems between the brain and the rest of the body. The study compares the effects of …
This study investigates the effectiveness and safety of an investigational medication for people with moderate to severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes itchy and inflamed skin. The study will compare the investigational medication to a placebo, which is an inactive substance that looks like …
This study investigates the effectiveness of an investigational medication in delaying the progression of disability in individuals with non-relapsing Secondary Progressive Multiple Sclerosis (nrSPMS). nrSPMS is a stage of multiple sclerosis where the disease steadily worsens without relapses. Participants will be randomly assigned to receive either the investigational medication or …
An investigational medication is what is being studied to see if symptoms improve while taking it. It is not yet approved for general use by regulatory authorities. This study uses an investigational medication called Riliprubart. The investigational medicine is injected in a vein or under the skin, either at the …
This study investigates chronic graft versus host disease (cGVHD), a condition where transplanted donor cells attack the recipient's body after a stem cell or bone marrow transplant. cGVHD involves immune responses and tissue scarring, affecting various organs. The purpose of this study is to evaluate whether adding an investigational medication …
This study investigates the treatment of moderate-to-severe atopic dermatitis (AD) in participants aged 12 years and older. Atopic dermatitis, also known as eczema, is a condition that makes the skin red, inflamed, and itchy. The purpose of this study is to evaluate the effectiveness and safety of an investigational medication …
This study investigates an investigational medication to see if it can improve breathing and symptoms of asthma while reducing future asthma attacks. Asthma is a condition where the airways in the lungs become narrow and inflamed, making it hard to breathe. This study is looking at how well the investigational …
