This study investigates the safety and immune response of a single injection of a hexavalent influenza mRNA vaccine in adults aged 50 and older. The investigational vaccine contains components targeting six different flu virus strains. The study compares different formulations of this vaccine to a standard flu vaccine. The purpose …
This study investigates the use of an investigational medication for erectile dysfunction. Erectile dysfunction is when someone has trouble getting or keeping an erection. The study will look at whether participants can properly choose and use the medication by following the instructions on the label and completing a health survey. …
This study investigates the safety and how well the body responds to two different pneumococcal vaccines in infants, toddlers, and children. Pneumococcal vaccines help protect against infections caused by the bacteria Streptococcus pneumoniae, which can lead to illnesses like pneumonia. The study involves comparing an investigational vaccine to an existing …
This study investigates the effects of an investigational medication on adults with moderate to severe atopic dermatitis, a skin condition characterized by red, inflamed, and itchy skin. Atopic dermatitis is a chronic condition that can significantly impact a person's quality of life.Participants in the study will receive either the investigational …
This study investigates how an investigational medication affects the response to vaccines in adults with moderate-to-severe atopic dermatitis. Atopic dermatitis is a skin condition causing red, itchy patches. The purpose of this study is to compare how well participants' immune systems respond to two vaccines, Tdap and PPSV, when they …
This study investigates the safety and effectiveness of an investigational medication in male and female participants aged 12 years and older with chronic graft-versus-host disease (cGVHD). cGVHD is a condition where the donated cells from a transplant attack the recipient's body. The study focuses on individuals who identify as Black …
This study investigates the long-term effects of an investigational medication on skin barrier function in children with atopic dermatitis (AD). Atopic dermatitis is a condition that makes the skin red, itchy, and inflamed. The study will look at how the skin loses water, which is called transepidermal water loss, before …
This study investigates an investigational vaccine for acne, a common inflammatory skin condition that affects many people worldwide, especially teenagers and young adults. Acne causes pimples, blackheads, and other skin issues. The purpose of this study is to learn about the safety, effectiveness, and the body's immune response to different …
This study investigates the safety and tolerability of an investigational medication combined with other agents in people with certain blood cancers that express a protein called CD123. Hematological malignancies are types of cancer that begin in blood-forming tissue, such as the bone marrow, or in the cells of the immune …
This study investigates the effects of an investigational medication on adults with moderate-to-severe ulcerative colitis (UC). Ulcerative colitis is a long-term condition that causes inflammation and sores in the digestive tract, particularly affecting the lining of the large intestine and rectum. The purpose of this study is to evaluate how …
