This study investigates the effects of an investigational medication in adults with relapsing forms of multiple sclerosis (MS). The purpose of the study is to compare the annualized relapse rate (ARR) of participants taking the investigational medication versus those taking a daily oral dose of another medication.Participants will undergo regular …
This study investigates the long-term safety and efficacy of an investigational subcutaneous treatment for individuals aged 12 and older with moderate to severe atopic dermatitis (AD). The study aims to understand how the treatment works over an extended period, focusing on participants who have not responded well to other treatments.Participants …
This study investigates the effect of an investigational medication, an Anti-OX40L Monoclonal Antibody, in adults with moderate to severe atopic dermatitis. The study will compare the investigational medication to other treatment arms to assess its effectiveness.Participants will be randomly assigned to one of five study arms in a double-blind manner, …
This study investigates the safety and effectiveness of an investigational medication in participants with chronic graft versus host disease (cGVHD). The study focuses on Black or African American, American Indian or Alaska Native, and Native Hawaiian or Other Pacific Islander participants who have already been treated with at least two …
This study investigates the effects of switching from emicizumab to an investigational medication for individuals with severe hemophilia A. The purpose of this study is to understand the safety and tolerability of the investigational medication after participants transition from their current preventive treatment.Participants will undergo a screening period followed by …
This study investigates the safety, efficacy, and immune response of an investigational mRNA vaccine for adults with moderate to severe acne. This study aims to evaluate how well the vaccine works at different doses in participants aged 18 to 45 years.Participants in the study will receive up to three intramuscular …
This study investigates the long-term effects of an investigational medication in adults with Alpha-1 Antitrypsin Deficiency (AATD) emphysema. The purpose of this study is to understand how the investigational medication affects individuals with this condition over an extended period.Participants in this study will receive the investigational medication and will be …
This study investigates the use of a subcutaneous delivery system for a combination of investigational medication, carfilzomib, and dexamethasone in adults with relapsed or refractory multiple myeloma. The purpose of this study is to evaluate the overall response rate to this treatment combination in participants who have previously undergone one …
This study investigates the effectiveness of different investigational medications compared to a placebo in improving lung capacity in participants with Interstitial Lung Disease (ILD) secondary to Systemic Sclerosis (SSc). The purpose is to observe changes from the start to the end of the treatment period at Week 52.Participants in the …
This study investigates the safety and effects of an investigational mRNA vaccine for individuals with mild acne. The study will include two groups, a Sentinel Cohort to initially assess safety, and a Main Cohort for broader evaluation.Participants will receive two administrations of the investigational vaccine. The study will consist of …
