This study investigates the long-term safety and efficacy of an investigational medication in adult participants with asthma. Participants who have completed previous studies with the investigational medication are eligible to join this extended study.Participants will receive the investigational medication and continue their background therapy, which may include inhaled corticosteroids and …
This study investigates the effects of an investigational medication compared to a placebo in adults with Chronic Obstructive Pulmonary Disease (COPD) that is not well controlled and is characterized by an eosinophilic phenotype. An eosinophilic phenotype refers to a certain type of inflammation in the lungs, which can affect how …
This study investigates the efficacy and safety of an investigational medication in patients with moderate to severe Crohn's disease. The study involves different doses of the investigational medication compared to a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.Participants will …
This study investigates the impact of an investigational medication compared to standard care on lung function in adults with uncontrolled moderate to severe asthma. This study aims to determine if the investigational medication can prevent or slow down the decline in lung function.Participants in the study will be randomly assigned …
This study investigates the effects of an investigational medication compared to a placebo in adults with chronic obstructive pulmonary disease (COPD) that is not well controlled and is characterized by a higher number of eosinophils, a type of white blood cell. The purpose of this study is to assess how …
This study investigates the effect of an investigational medication, an Anti-OX40L Monoclonal Antibody, in adults with moderate to severe atopic dermatitis. The study will compare the investigational medication to other treatment arms to assess its effectiveness.Participants will be randomly assigned to one of five study arms in a double-blind manner, …
This study investigates the safety and effectiveness of an investigational medication in participants with chronic graft versus host disease (cGVHD). The study focuses on Black or African American, American Indian or Alaska Native, and Native Hawaiian or Other Pacific Islander participants who have already been treated with at least two …
This study investigates the effects of switching from emicizumab to an investigational medication for individuals with severe hemophilia A. The purpose of this study is to understand the safety and tolerability of the investigational medication after participants transition from their current preventive treatment.Participants will undergo a screening period followed by …
This study investigates the safety, efficacy, and immune response of an investigational mRNA vaccine for adults with moderate to severe acne. This study aims to evaluate how well the vaccine works at different doses in participants aged 18 to 45 years.Participants in the study will receive up to three intramuscular …
This study investigates the long-term effects of an investigational medication in adults with Alpha-1 Antitrypsin Deficiency (AATD) emphysema. The purpose of this study is to understand how the investigational medication affects individuals with this condition over an extended period.Participants in this study will receive the investigational medication and will be …
