This study investigates the safety and effectiveness of an investigational medication in male and female participants aged 12 years and older with chronic graft-versus-host disease (cGVHD). cGVHD is a condition where the donated cells from a transplant attack the recipient's body. The study focuses on individuals who identify as Black …
This study investigates an investigational vaccine for acne, a common inflammatory skin condition that affects many people worldwide, especially teenagers and young adults. Acne causes pimples, blackheads, and other skin issues. The purpose of this study is to learn about the safety, effectiveness, and the body's immune response to different …
This study investigates the safety and tolerability of an investigational medication combined with other agents in people with certain blood cancers that express a protein called CD123. Hematological malignancies are types of cancer that begin in blood-forming tissue, such as the bone marrow, or in the cells of the immune …
This study investigates the effects of an investigational medication given with other treatments to adults with relapsed or refractory multiple myeloma (RRMM). Multiple myeloma is a cancer of the plasma cells in the bone marrow. The purpose of this study is to assess how well the investigational medication works when …
This study investigates the effects of an investigational medication on adults with moderate-to-severe atopic dermatitis (AD). Atopic dermatitis is a chronic skin condition that causes itchy and inflamed skin. This study is for adults aged 18 to 80 who have not had success with topical treatments or cannot use them. …
This study investigates the effects of investigational medications compared to a placebo on lung capacity in people with Interstitial Lung Disease (ILD) caused by Systemic Sclerosis (SSc). Systemic Sclerosis is a condition where the skin and other organs become hard and thick due to increased collagen. The study aims to …
This study investigates the efficacy and safety of an investigational medication in participants with sickle-cell disease (SCD). Sickle-cell disease is a genetic condition where red blood cells, which normally look like discs, become crescent-shaped. These sickle-shaped cells can block blood flow and cause pain and other serious problems. The study …
This study investigates the effects of an investigational medication on adults with moderate-to-severe ulcerative colitis (UC). Ulcerative colitis is a long-term condition that causes inflammation and sores in the digestive tract, particularly affecting the lining of the large intestine and rectum. The purpose of this study is to evaluate how …
This study investigates the effects of vaccination during pregnancy on mothers and their babies. It looks at the health outcomes for both the mothers and their newborns when the mothers receive a vaccine called an investigational vaccine during pregnancy. The study aims to understand how this vaccine affects both maternal …
This study investigates the clinical outcomes of patients with Gaucher disease, a genetic disorder where fatty substances build up in certain organs, particularly the spleen and liver. The study is observational, meaning it does not involve any experimental treatments. Instead, it aims to understand the variability, progression, and natural history …
