This study investigates the efficacy, safety, and tolerability of an investigational medication given as a subcutaneous injection compared to a placebo in adults with chronic obstructive pulmonary disease (COPD). COPD is a long-term lung disease that causes breathing difficulties. This study focuses on participants who have an eosinophilic phenotype, which …
This study investigates the effects of an investigational medication, administered subcutaneously, in adults with Chronic Obstructive Pulmonary Disease (COPD) characterized by an eosinophilic phenotype. COPD is a chronic lung disease that causes breathing difficulties and is often associated with long-term exposure to harmful substances like cigarette smoke. The study aims …
This study investigates the effects of an investigational medication on adults with moderate to severe atopic dermatitis, a skin condition characterized by red, inflamed, and itchy skin. Atopic dermatitis is a chronic condition that can significantly impact a person's quality of life.Participants in the study will receive either the investigational …
This study investigates the safety and effectiveness of an investigational medication in male and female participants aged 12 years and older with chronic graft-versus-host disease (cGVHD). cGVHD is a condition where the donated cells from a transplant attack the recipient's body. The study focuses on individuals who identify as Black …
This study investigates the safety of switching to an investigational medication after stopping another treatment called emicizumab. The purpose of this study is to understand how male participants with severe hemophilia A, a condition where blood does not clot properly, respond to this change in treatment. Hemophilia A is a …
This study investigates the long-term safety and effects of an investigational medication in adults with Alpha-1 Antitrypsin Deficiency (AATD) emphysema. AATD is a genetic condition that can lead to lung diseases like emphysema. Emphysema is a lung condition that causes shortness of breath due to damaged air sacs in the …
This study investigates the effects of an investigational medication given with other treatments to adults with relapsed or refractory multiple myeloma (RRMM). Multiple myeloma is a cancer of the plasma cells in the bone marrow. The purpose of this study is to assess how well the investigational medication works when …
This study investigates the effects of investigational medications compared to a placebo on lung capacity in people with Interstitial Lung Disease (ILD) caused by Systemic Sclerosis (SSc). Systemic Sclerosis is a condition where the skin and other organs become hard and thick due to increased collagen. The study aims to …
This study investigates the effects of an investigational medication on individuals with non-congenital myotonic dystrophy type 1 (DM1). DM1 is a genetic disorder that causes muscle weakness and myotonia, which is difficulty in relaxing muscles after they contract. The purpose of this study is to see if the investigational medication …
This study investigates the safety and immune response of an investigational vaccine for individuals with mild acne. Acne is a common skin condition characterized by pimples, blackheads, and whiteheads. The study will assess the effects of two doses of the vaccine in adults aged 18 to 45 years.Participants will be …
