This study investigates the effects of adding an investigational medication to the treatment of patients with uncontrolled asthma. Uncontrolled asthma means that patients still experience frequent symptoms despite taking their current asthma medication.The study focuses on evaluating the effectiveness of the investigational medication when used alongside inhaled asthma treatments. It …
This study investigates the administration of an investigational medication for people with multiple sclerosis (MS). The purpose is to compare two ways of giving the medication: under the skin (subcutaneous) and into the vein (intravenous).The study focuses on understanding how these two methods of administration affect the treatment of MS. …
This study investigates the consistency of a 21-valent pneumococcal conjugate vaccine in healthy infants. The purpose is to see if three different lots of this investigational vaccine can produce a similar immune response in infants aged around 2 months.The study focuses on evaluating the safety and immune response of the …
This study investigates the safety, efficacy, and immune response of an investigational mRNA vaccine for adults aged 18 to 45 with moderate to severe acne. This study aims to explore new possibilities for treating this condition with a vaccine approach.The study focuses on evaluating how well the investigational mRNA vaccine …
This study investigates the effect of an investigational medication, an Anti-OX40L Monoclonal Antibody, in adults with moderate to severe atopic dermatitis. The study will compare the investigational medication to other treatment arms to assess its effectiveness.Participants will be randomly assigned to one of five study arms in a double-blind manner, …
This study investigates the effects of switching from emicizumab to an investigational medication for individuals with severe hemophilia A. The purpose of this study is to understand the safety and tolerability of the investigational medication after participants transition from their current preventive treatment.Participants will undergo a screening period followed by …
This study investigates the use of an investigational medication in combination with other treatments for adults who have relapsed or refractory multiple myeloma.The study focuses on evaluating the effectiveness of this combination treatment. Researchers aim to understand how well the treatment works in improving the condition of participants who have …
This study investigates the effectiveness of different investigational medications compared to a placebo in improving lung capacity in participants with Interstitial Lung Disease (ILD) secondary to Systemic Sclerosis (SSc). The purpose is to observe changes from the start to the end of the treatment period at Week 52.Participants in the …
This study investigates the safety and effects of an investigational mRNA vaccine for individuals with mild acne. The study will include two groups, a Sentinel Cohort to initially assess safety, and a Main Cohort for broader evaluation.Participants will receive two administrations of the investigational vaccine. The study will consist of …
This study investigates a treatment for geographic atrophy, a condition related to age-related macular degeneration (AMD). The purpose of this study is to assess the safety and effectiveness of a one-time injection in the eye for people with geographic atrophy. The study will look at how well the treatment works …
