This study investigates the long-term safety and tolerability of an investigational medication in adults with multiple sclerosis (MS). Participants in this study have previously been part of earlier trials of the investigational medication.Participants will continue or start open-label treatment with the investigational medication, depending on their previous study involvement. Some …
This study investigates the treatment response and safety of two dose regimens of an investigational medication compared with treatment withdrawal in individuals aged 12 years and older with moderate-to-severe atopic dermatitis. The study aims to see if participants who responded to the investigational medication in earlier studies can maintain their …
This study investigates the effectiveness and safety of three investigational medications compared to a placebo in treating primary focal segmental glomerulosclerosis (FSGS) or primary minimal change disease (MCD). These kidney disorders can lead to nephrotic syndrome, characterized by high levels of protein in the urine (proteinuria). The purpose of this …
This study investigates the long-term safety and efficacy of an investigational medication in adult participants with asthma. Participants who have completed previous studies with the investigational medication are eligible to join this extended study.Participants will receive the investigational medication and continue their background therapy, which may include inhaled corticosteroids and …
This study investigates the safety and efficacy of an investigational medication injected under the skin in adult participants with relapsed or refractory multiple myeloma. This study aims to determine the best dose of the investigational medication for future research.Participants will be involved in two parts of the study. In Part …
This study investigates the ability of participants to appropriately select and use an investigational medication for erectile dysfunction using specific labeling and a health survey assessment (HSA). The study will enroll men interested in an over-the-counter treatment for this condition.Participants will enter the study through an open-label process, meaning both …
This study investigates the effects of an investigational medication given once a week to people with Hemophilia A who have joint swelling known as synovial hypertrophy. Participants in this study will receive the investigational medication once a week for about 12 months. During the study, doctors will monitor the participants' …
This study investigates the efficacy and safety of an investigational medication in patients with moderate to severe Crohn's disease. The study involves different doses of the investigational medication compared to a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.Participants will …
This study investigates the effects and safety of an investigational medication in adults with Graves' disease. Some participants may also have Graves' orbitopathy, which affects the eyes.Participants in this study will be assigned to one of two study arms, each receiving a different dose of the investigational medication. The study …
This study investigates the efficacy and safety of an investigational medication in people with moderately to severely active Crohn's Disease (CD). The study is divided into three sub-studies to evaluate how well the medication works and how safe it is for participants.Participants in the study may undergo several procedures, including …
