This study investigates the safety and preliminary effects of SAR445877, an investigational medication, in adults with advanced solid tumors that cannot be removed by surgery or have spread to other parts of the body. The study is divided into two parts. In Part 1, researchers will determine safe doses for …
This study investigates the long-term safety and how well an investigational medication works in people with moderate to severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes itchy and inflamed skin. The study is for participants who are 12 years or older.Participants will receive the investigational medication …
This study investigates the safety and efficacy of three different dose levels of an investigational medication compared to a placebo in people with newly diagnosed Type 1 Diabetes (T1D) who are on insulin treatment. Type 1 diabetes is a chronic disease where the body's defense system mistakenly attacks specific cells …
This study investigates the effects of an investigational medication on adults with moderate to severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes red, itchy, and inflamed skin. Participants in this study have AD that is not well controlled by topical treatments or cannot use such treatments …
This study investigates the safety and effectiveness of an investigational medication in children aged 2 to under 6 years who have uncontrolled asthma or experience frequent severe wheezing. Uncontrolled asthma means that the usual treatments are not enough to manage the symptoms. The study is divided into two parts. Part …
This study investigates the effects of an investigational medication for people with moderate-to-severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes itchy, inflamed skin. The study focuses on participants aged 12 years and older who have not responded well to previous treatments, including biologic medications or oral …
This study investigates the long-term safety and tolerability of an investigational medication in adults with different types of multiple sclerosis (MS), such as relapsing MS (RMS), primary progressive MS (PPMS), and non-relapsing secondary progressive MS (NRSPMS). Multiple sclerosis is a condition where the immune system mistakenly attacks the protective covering …
The purpose of this study is to investigate the effectiveness of an investigational medication for individuals with moderate-to-severe atopic dermatitis, a skin condition that causes itchy and inflamed skin. This study is designed for participants who have previously responded to a specific treatment in earlier studies and will examine if …
This study investigates the long-term safety and effects of an investigational medication in adults with Alpha-1 Antitrypsin Deficiency (AATD) emphysema. AATD is a genetic condition that can lead to lung diseases like emphysema. Emphysema is a lung condition that causes shortness of breath due to damaged air sacs in the …
This study investigates the effects of investigational medications on primary focal segmental glomerulosclerosis (FSGS) and primary minimal change disease (MCD). FSGS and MCD are kidney disorders that cause proteinuria, which is an excess of protein in the urine. The purpose of this study is to see how these investigational medications …
