This study investigates the effects and safety of an investigational medication in children aged 2 to less than 6 years who have uncontrolled asthma or severe asthmatic wheeze. The purpose is to understand how well the medication works and how safe it is for long-term use in this age group. …
This study investigates the safety and preliminary effectiveness of an investigational medication for adults with advanced solid tumors that cannot be surgically removed or have spread to other parts of the body. The study consists of two parts: a dose escalation phase to find the appropriate dose of the investigational …
This study investigates the safety and efficacy of an investigational gene therapy for individuals with non-congenital myotonic dystrophy type 1 (DM1). The purpose of this study is to assess how well the investigational therapy can reduce levels of a specific protein linked to DM1 and improve muscle function in participants …
This study investigates the effectiveness of adding an investigational medication to the treatment regimen of patients with uncontrolled asthma. Uncontrolled asthma refers to patients who continue to experience frequent symptoms despite their current medication. The study compares two treatment arms: one where participants receive the investigational medication along with their …
This study investigates the long-term safety and efficacy of an investigational medication in adults with asthma. It is an extension of previous studies and will last up to 100 weeks, with participants receiving treatment for up to 96 weeks. The purpose of this study is to continue monitoring the effects …
This study investigates the treatment of Systemic Lupus Erythematosus (SLE) using an investigational medication compared to a placebo. Participants will be involved in the study for a total of 36 weeks, with the treatment phase lasting 24 weeks. This means that individuals will participate in the study for over half …
This study investigates the treatment of moderate-to-severe atopic dermatitis in participants aged 12 years and older. The purpose is to evaluate the efficacy and safety of an investigational medication given as a subcutaneous injection, compared to a placebo. Participants will continue using their topical corticosteroids (TCS) during the study. The …
This study investigates chronic graft versus host disease (cGVHD) in children who have undergone a stem cell or bone marrow transplant. The purpose of this study is to understand how the investigational medication works in children with moderate to severe cGVHD. Participants will be in the study for up to …
This study investigates the treatment of immune thrombocytopenia (ITP) in adults who did not respond to first-line treatments. The purpose is to evaluate the effects of a new investigational medication. Participants will be in the study for a total of 60 weeks. This includes a screening period of up to …
This study investigates the effects of investigational medications on primary focal segmental glomerulosclerosis (FSGS) and primary minimal change disease (MCD). The purpose of this study is to measure the change in proteinuria and its impact on the rates of remission of nephrotic syndrome in participants aged 16 to 75 years.Participants …
