This study investigates the effectiveness and safety of an investigational medication in people with moderately to severely active Ulcerative Colitis (UC). Participants will be randomly assigned to different study arms, including a placebo group, to assess the investigational medication's impact. This study includes various procedures like screening, treatment periods, and …
This study investigates the safety and effectiveness of a one-time intravitreal dose of an investigational medication in adults with neovascular age-related macular degeneration (nAMD). The study is conducted in two parts: Part I involves evaluating different dose levels in successive groups of participants, while Part II involves randomizing participants to …
This study investigates the pharmacokinetics and safety of an investigational medication in children aged 6 months to under 18 years with prurigo nodularis. The purpose of the study is to understand how the investigational medication is processed in the body and to assess its safety for the participants.Participants in the …
This study investigates the effects of a single oral dose of an investigational medication on cardiac repolarization in healthy adults. The study is a Phase 1 trial, meaning it is an early stage of testing, and involves several different treatment arms to compare the investigational medication with a placebo and …
This study investigates eosinophilic esophagitis (EoE), an inflammatory disease of the esophagus that affects feeding and nourishment. The purpose of this study is to assess the safety, tolerability, and effectiveness of an investigational medication in children with active EoE over a period of 24 weeks.Participants will receive the investigational medication …
This study investigates chronic inflammatory demyelinating polyneuropathy (CIDP), focusing on individuals with residual impairment or disability after receiving standard treatments for at least three months. The purpose of this observational study is to collect data on people with CIDP to better understand how treatments work in real-world settings.Participants will continue …
This study investigates the outcomes for mothers and their babies when the mothers receive the investigational vaccine during pregnancy. The focus is on understanding how the vaccine affects maternal health, pregnancy progress, and the newborn's health. Outcomes will be closely monitored to gather important data on these aspects.Participants in the …
This study investigates eosinophilic esophagitis (EoE). The purpose of this study is to observe patients with EoE who have recently started treatment with an investigational medication as part of their regular care.Participants will complete questionnaires about their experiences with EoE. These will cover topics such as how EoE affects their …
This study investigates the use of an investigational medication in combination with other novel agents in participants with relapsed or refractory multiple myeloma (RRMM). The study includes several substudies with different combinations of treatments, some with and some without the drug dexamethasone.Participants in this study will undergo various procedures depending …
This study investigates the effects of an investigational medication on preventing or slowing lung function decline in adults with uncontrolled moderate to severe asthma. Participants in this study will be randomly assigned to one of two study arms: one receiving the investigational medication and the other receiving standard care therapy.Participants …
