This study investigates the effectiveness and safety of an investigational medication compared to a placebo in treating chronic lung allograft dysfunction (CLAD) in adults who have had a lung transplant. Participants in this study must have had their transplant at least a year ago and must be experiencing progression of …
This study investigates the safety and effectiveness of a one-time intravitreal dose of an investigational medication in adults with neovascular age-related macular degeneration (nAMD). The study is conducted in two parts: Part I involves evaluating different dose levels in successive groups of participants, while Part II involves randomizing participants to …
This study investigates the pharmacokinetics and safety of an investigational medication in children aged 6 months to under 18 years with prurigo nodularis. The purpose of the study is to understand how the investigational medication is processed in the body and to assess its safety for the participants.Participants in the …
This study investigates the effects of a single oral dose of an investigational medication on cardiac repolarization in healthy adults. The study is a Phase 1 trial, meaning it is an early stage of testing, and involves several different treatment arms to compare the investigational medication with a placebo and …
This study investigates an investigational medication in children with eosinophilic esophagitis (EoE). Participants will receive the investigational medication for 24 weeks. The study will monitor for any side effects, measure the amount of medication in the blood at various times, and check if the body develops antibodies against the medication, …
This study investigates chronic inflammatory demyelinating polyneuropathy (CIDP), focusing on individuals with residual impairment or disability after receiving standard treatments for at least three months. The purpose of this observational study is to collect data on people with CIDP to better understand how treatments work in real-world settings.Participants will continue …
This study investigates eosinophilic esophagitis (EoE) and aims to observe how patients with EoE are treated with an investigational medication as part of their routine care.Participants will complete questionnaires about their experience with EoE, including how it affects their symptoms, quality of life, and daily activities. These questionnaires will help …
This study investigates the outcomes of pregnancy and infant health when women receive an investigational vaccine during pregnancy. The purpose is to assess how the vaccine affects maternal health, pregnancy, and the health of newborns and infants up to one year of age.Participants in this study will be monitored throughout …
This study investigates the use of an investigational medication in combination with other novel agents in participants with relapsed or refractory multiple myeloma (RRMM). The study includes several substudies with different combinations of treatments, some with and some without the drug dexamethasone.Participants in this study will undergo various procedures depending …
This study investigates the effects of an investigational medication on preventing or slowing lung function decline in adults with uncontrolled moderate to severe asthma. Participants in this study will be randomly assigned to one of two study arms: one receiving the investigational medication and the other receiving standard care therapy.Participants …
