This study investigates the safety and effectiveness of a one-time intravitreal dose of an investigational medication in adults with neovascular age-related macular degeneration (nAMD). The study is conducted in two parts: Part I involves evaluating different dose levels in successive groups of participants, while Part II involves randomizing participants to …
This study investigates the effects of a single oral dose of an investigational medication on cardiac repolarization in healthy adults. The study is a Phase 1 trial, meaning it is an early stage of testing, and involves several different treatment arms to compare the investigational medication with a placebo and …
This study investigates the effects of an investigational medication in children who have eosinophilic esophagitis. The purpose of this study is to understand how this condition impacts young children.The study focuses on evaluating the safety, tolerability, and effectiveness of the investigational medication over a period of time. Researchers are also …
This study investigates the outcomes for mothers and their babies when the mothers receive the investigational vaccine during pregnancy. The focus is on understanding how the vaccine affects maternal health, pregnancy progress, and the newborn's health. Outcomes will be closely monitored to gather important data on these aspects.Participants in the …
This study investigates chronic inflammatory demyelinating polyneuropathy (CIDP), focusing on individuals with residual impairment or disability after receiving standard treatments for at least three months. The purpose of this observational study is to collect data on people with CIDP to better understand how treatments work in real-world settings.Participants will continue …
This study investigates eosinophilic esophagitis (EoE) in patients who have been prescribed an investigational medication as part of their standard care. The purpose is to understand the experiences of these patients and how the condition affects them.The study focuses on observing how the investigational medication is used in routine care …
This study investigates the use of an investigational medication in combination with other novel agents in participants with relapsed or refractory multiple myeloma (RRMM). The study includes several substudies with different combinations of treatments, some with and some without the drug dexamethasone.Participants in this study will undergo various procedures depending …
This study investigates the long-term effects of an investigational medication on preventing the decline of lung function in adults with uncontrolled moderate to severe asthma.The focus of the study is to evaluate the effectiveness of the investigational medication compared to standard care in slowing down the deterioration of lung function. …
This study investigates the effectiveness and safety of an investigational medication for adults with chronic pruritus of unknown origin (CPUO). The study aims to understand how well the investigational medication works in reducing the symptoms of CPUO.The focus of this study is to evaluate the investigational medication's impact on the …
This study investigates the safety and preliminary effectiveness of an investigational medication for adults with advanced solid tumors that cannot be surgically removed or have spread to other parts of the body. The study consists of two parts: a dose escalation phase to find the appropriate dose of the investigational …
