This study investigates the effects of an investigational medication in adults with non-responsive celiac disease (NRCD) who follow a gluten-free diet. This study aims to understand how the investigational medication affects intestinal damage caused by gluten exposure, as measured by the villous height to crypt depth ratio, and its impact …
This study investigates the effectiveness and safety of an investigational medication compared to a placebo in treating chronic lung allograft dysfunction (CLAD) in adults who have had a lung transplant. Participants in this study must have had their transplant at least a year ago and must be experiencing progression of …
This study investigates the improvement of itching in individuals with Lichen Simplex Chronicus (LSC) using subcutaneous injections of an investigational medication compared to placebo. The study involves male and female participants who are 18 years or older and have moderate-to-severe LSC.Participants in the study will receive either the investigational medication …
This study investigates the effect of an investigational medication on reducing itchiness in individuals with Lichen Simplex Chronicus (LSC). The purpose of this study is to compare the effectiveness of the investigational medication given by injection to a placebo in adults aged 18 and over who have moderate-to-severe LSC.Participants will …
This study investigates the safety and ability of an investigational pneumococcal conjugate vaccine to stimulate the immune system in healthy infants. Infants between 42 and 89 days old will receive either the investigational vaccine or a licensed pneumococcal vaccine, alongside routine pediatric vaccines. The purpose is to compare the immune …
This study investigates the safety of an investigational pneumococcal vaccine in healthy infants aged approximately 2 months. The purpose is to compare its safety profile to a licensed 20-valent pneumococcal conjugate vaccine. Infants participating in the study will receive either the investigational vaccine or the licensed vaccine as part of …
This study investigates the safety and immune response of an investigational pneumococcal conjugate vaccine, referred to as PCV21, in infants. The purpose is to determine if PCV21 can stimulate the production of antibodies when administered after one, two, or three doses of a licensed 20-valent pneumococcal vaccine. This is compared …
This study investigates the long-term safety and effectiveness of an investigational medication in adults with chronic inflammatory demyelinating polyneuropathy (CIDP). This study is an extension for those who have completed certain previous studies and wish to continue treatment with the investigational medication.Participants in this study will receive weekly doses of …
The purpose of this study is to investigate the efficacy and safety of an investigational medication in participants with moderately to severely active Ulcerative Colitis (UC). This study includes different arms to evaluate the investigational medication in various scenarios.Participants will undergo procedures such as screening and treatment over several weeks. …
This study investigates the efficacy and safety of an investigational medication in individuals with moderately to severely active ulcerative colitis.Participants will be randomly assigned to receive either the investigational medication or a placebo. A placebo is an inactive substance that looks like the investigational medicine but does not contain any …
