This study investigates the effects of an investigational medication compared to a placebo in adults with high-risk asthma. The purpose of this study is to evaluate how well the investigational medication works, as well as its safety and tolerability, when added to the current treatment of asthma. Participants in this …
This study investigates the efficacy and safety of an investigational medication in treating Systemic Lupus Erythematosus (SLE). Participants will be randomly assigned to one of two study arms: one receiving the investigational medication and the other receiving a placebo, which is an inactive substance that looks like the investigational medication …
This study investigates the effectiveness and safety of an investigational medication compared to a placebo in treating chronic lung allograft dysfunction (CLAD) in adults who have had a lung transplant. Participants in this study must have had their transplant at least a year ago and must be experiencing progression of …
This study investigates the safety and ability of an investigational pneumococcal conjugate vaccine to stimulate the immune system in healthy infants. Infants between 42 and 89 days old will receive either the investigational vaccine or a licensed pneumococcal vaccine, alongside routine pediatric vaccines. The purpose is to compare the immune …
This study investigates the safety of an investigational pneumococcal vaccine in healthy infants aged approximately 2 months. The purpose is to compare its safety profile to a licensed 20-valent pneumococcal conjugate vaccine. Infants participating in the study will receive either the investigational vaccine or the licensed vaccine as part of …
This study investigates the safety and immune response of an investigational pneumococcal conjugate vaccine, referred to as PCV21, in infants. The purpose is to determine if PCV21 can stimulate the production of antibodies when administered after one, two, or three doses of a licensed 20-valent pneumococcal vaccine. This is compared …
This study investigates chronic rhinosinusitis with nasal polyps (CRSwNP). The purpose of this study is to evaluate the effectiveness, safety, and tolerability of two dosing regimens of an investigational medication, compared to a placebo, as an additional treatment to standard intranasal corticosteroids in people with CRSwNP.Participants in the study will …
This study investigates the long-term safety, tolerability, and effectiveness of an investigational medication in adults with chronic rhinosinusitis with nasal polyps (CRSwNP). Participants in this study have previously completed a related clinical study.Participants will receive the investigational medication and will continue using an intranasal spray as part of the study …
The purpose of this study is to investigate the efficacy and safety of an investigational medication in participants with moderately to severely active Ulcerative Colitis (UC). This study includes different arms to evaluate the investigational medication in various scenarios.Participants will undergo procedures such as screening and treatment over several weeks. …
This study investigates the efficacy and safety of an investigational medication in individuals with moderately to severely active ulcerative colitis.Participants will be randomly assigned to receive either the investigational medication or a placebo. A placebo is an inactive substance that looks like the investigational medicine but does not contain any …
