This study investigates the effectiveness and safety of an investigational medication in treating adults with Chronic Pruritus of Unknown Origin (CPUO). Pruritus is a medical term for severe itching. The study includes two parts, Study A and Study B, involving male and female participants aged 18 to 90 years. Participants …
This study investigates the safety and effects of an investigational medication in people with HER2+ tumors, which are tumors that have a protein called Human Epidermal Growth Factor Receptor 2. This protein can promote the growth of cancer cells and is found in some types of cancer. The study is …
This study investigates the safety and effectiveness of an investigational medication in people with moderate to severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes red, itchy, and inflamed skin. Participants in this study have previously been treated with the investigational medication in earlier trials. The study …
This study investigates the safety and preliminary effects of SAR445877, an investigational medication, in adults with advanced solid tumors that cannot be removed by surgery or have spread to other parts of the body. The study is divided into two parts. In Part 1, researchers will determine safe doses for …
This study investigates the long-term safety and how well an investigational medication works in people with moderate to severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes itchy and inflamed skin. The study is for participants who are 12 years or older.Participants will receive the investigational medication …
This study investigates the safety and efficacy of three different dose levels of an investigational medication compared to a placebo in people with newly diagnosed Type 1 Diabetes (T1D) who are on insulin treatment. Type 1 diabetes is a chronic disease where the body's defense system mistakenly attacks specific cells …
This study investigates the safety and effectiveness of an investigational medication in children aged 2 to under 6 years who have uncontrolled asthma or experience frequent severe wheezing. Uncontrolled asthma means that the usual treatments are not enough to manage the symptoms. The study is divided into two parts. Part …
The purpose of this study is to investigate the effectiveness of an investigational medication for individuals with moderate-to-severe atopic dermatitis, a skin condition that causes itchy and inflamed skin. This study is designed for participants who have previously responded to a specific treatment in earlier studies and will examine if …
This study investigates the long-term safety and effects of an investigational medication in adults with Alpha-1 Antitrypsin Deficiency (AATD) emphysema. AATD is a genetic condition that can lead to lung diseases like emphysema. Emphysema is a lung condition that causes shortness of breath due to damaged air sacs in the …
This study investigates the effects of investigational medications on primary focal segmental glomerulosclerosis (FSGS) and primary minimal change disease (MCD). FSGS and MCD are kidney disorders that cause proteinuria, which is an excess of protein in the urine. The purpose of this study is to see how these investigational medications …
