This study investigates the efficacy, safety, and tolerability of an investigational medication in participants with chronic rhinosinusitis with nasal polyps (CRSwNP). The study aims to compare two dosing regimens of the investigational medication with a placebo, in addition to standard treatment with intranasal corticosteroids.Participants will undergo a series of procedures …
This study investigates the treatment of moderate to severe hidradenitis suppurativa. Participants will be involved in the study for up to 60 weeks if they do not continue into the long-term extension study, or up to 52 weeks if they do. The purpose of this study is to assess the …
This study investigates chronic rhinosinusitis with nasal polyps (CRSwNP). The purpose of the study is to evaluate how effective and safe an investigational medication is when used with nasal sprays in adults with CRSwNP. Participants will be in the study for up to 76 weeks, which includes time for screening, …
This study investigates the safety and efficacy of an investigational medication injected under the skin in adult participants with relapsed or refractory multiple myeloma. This study aims to determine the best dose of the investigational medication for future research.Participants will be involved in two parts of the study. In Part …
This study investigates the effects and safety of an investigational medication in children aged 2 to less than 6 years who have uncontrolled asthma or severe asthmatic wheeze. The purpose is to understand how well the medication works and how safe it is for long-term use in this age group. …
This study investigates advanced solid tumors, focusing on the safety of an investigational medication, a type of antibody-drug conjugate (ADC), in participants with these challenging-to-treat cancers.Participants will take part in a study with five different parts. Parts A and B will focus on determining the appropriate dosage of the investigational …
This study investigates the efficacy and safety of an investigational medication in patients with moderate to severe Crohn's disease. The study aims to compare different doses of the investigational medication with a placebo, which is an inactive substance that looks like the investigational medication but does not contain any medicine.Participants …
This study investigates the safety and preliminary effectiveness of an investigational medication for adults with advanced solid tumors that cannot be surgically removed or have spread to other parts of the body. The study consists of two parts: a dose escalation phase to find the appropriate dose of the investigational …
This study investigates the treatment of Systemic Lupus Erythematosus (SLE) using an investigational medication compared to a placebo. Participants will be involved in the study for a total of 36 weeks, with the treatment phase lasting 24 weeks. This means that individuals will participate in the study for over half …
This study investigates the treatment of moderate-to-severe atopic dermatitis in participants aged 12 years and older. The purpose is to evaluate the efficacy and safety of an investigational medication given as a subcutaneous injection, compared to a placebo. Participants will continue using their topical corticosteroids (TCS) during the study. The …
