This study investigates the effects of an investigational medication compared to a placebo in adults with moderate to severe hidradenitis suppurativa (HS). HS is a chronic skin condition that causes small, painful lumps under the skin. These lumps can break open or form tunnels under the skin. The study involves …
This study investigates the efficacy and safety of an investigational medication compared to a placebo in patients who have undergone a bilateral lung transplant and have chronic lung allograft dysfunction (CLAD). CLAD is a condition where the lung function declines over time after a transplant. Participants must be at least …
This study investigates a meningococcal vaccine in children under 10 years old. Meningococcal disease is a serious illness caused by bacteria that can lead to infections in the brain and spinal cord. The purpose of this study is to compare two formulations of a new investigational vaccine with existing vaccines. …
This study investigates the effects of an investigational medication on pruritus, which is a severe itching sensation, in individuals with Lichen Simplex Chronicus (LSC). LSC is a skin condition characterized by thickened, itchy patches of skin. The study compares the investigational medication given through subcutaneous injections to placebo injections in …
This study investigates the effectiveness of an investigational medication compared to a placebo in treating pruritus, or severe itching, in adults with Lichen Simplex Chronicus (LSC). LSC is a skin condition characterized by thickened, itchy patches of skin. The purpose of this study is to see if the investigational medication …
This study investigates the effects of an investigational medication on adults with chronic rhinosinusitis without nasal polyps (CRSsNP). Chronic rhinosinusitis is a condition where the nasal passages and sinuses are inflamed for a long time, causing symptoms like nasal congestion and facial pain. The purpose of this study is to …
This study investigates the effects of an investigational medication for people with chronic rhinosinusitis with nasal polyps (CRSwNP). CRSwNP is a condition where the tissue inside the nose becomes swollen and forms small growths called polyps. The study compares two different doses of the investigational medication to a placebo, which …
This study investigates the effects of an investigational medication on people with chronic rhinosinusitis with nasal polyps (CRSwNP). CRSwNP is a condition where the lining of the nasal passages and sinuses becomes swollen, leading to the growth of polyps. The study will compare two different dosing regimens of the investigational …
This study investigates the use of an investigational medication in patients who have undergone or are about to undergo a kidney transplant and may experience antibody-mediated rejection (AMR). AMR is a condition where the body's immune system attacks the transplanted kidney. The purpose of this study is to evaluate how …
This study investigates the effects of an investigational medication on children and adolescents with Systemic Juvenile Idiopathic Arthritis (sJIA). Systemic Juvenile Idiopathic Arthritis is a type of arthritis that causes joint inflammation and fever in children. The purpose of the study is to understand how the investigational medication behaves in …