This study investigates the efficacy and safety of an investigational medication given as a subcutaneous injection for individuals aged 12 years and older with moderate-to-severe atopic dermatitis (AD). The study focuses on participants who have not responded adequately to prior biologic therapies or oral JAK inhibitors, while continuing their topical …
This study investigates the effectiveness and safety of an investigational medication compared to a placebo in treating chronic lung allograft dysfunction (CLAD) in adults who have had a lung transplant. Participants in this study must have had their transplant at least a year ago and must be experiencing progression of …
This study investigates the safety and immune response of an investigational vaccine for meningococcal disease in children under 10 years old. The purpose of this study is to evaluate two formulations of the investigational vaccine, comparing them to existing vaccines. The study is conducted in three stages: Stage 1 involves …
This study investigates the improvement of itching in individuals with Lichen Simplex Chronicus (LSC) using subcutaneous injections of an investigational medication compared to placebo. The study involves male and female participants who are 18 years or older and have moderate-to-severe LSC.Participants in the study will receive either the investigational medication …
This study investigates the effect of an investigational medication on reducing itchiness in individuals with Lichen Simplex Chronicus (LSC). The purpose of this study is to compare the effectiveness of the investigational medication given by injection to a placebo in adults aged 18 and over who have moderate-to-severe LSC.Participants will …
This study investigates the effects of an investigational medication in people with chronic rhinosinusitis with nasal polyps (CRSwNP). The purpose of this study is to evaluate how well the investigational medication works, how safe it is, and how well people tolerate it when added to standard treatment with intranasal corticosteroids.Participants …
This study investigates the effects of an investigational medication on individuals with chronic rhinosinusitis with nasal polyps (CRSwNP). The purpose of this study is to assess the efficacy, safety, and tolerability of two dosing regimens of the investigational medication compared to a placebo, alongside intranasal corticosteroids (INCS).Participants will be randomly …
This study investigates the long-term safety and effectiveness of an investigational medication in adults with chronic inflammatory demyelinating polyneuropathy (CIDP). This study is an extension for those who have completed certain previous studies and wish to continue treatment with the investigational medication.Participants in this study will receive weekly doses of …
This study investigates the efficacy and safety of an investigational medication in adults with moderate to severe Ulcerative Colitis. The study compares different doses of the investigational medication to a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.Participants will be …
This study investigates the use of an investigational medication in preventing and treating antibody-mediated rejection (AMR) in kidney transplant patients. The study includes two arms: Cohort A focuses on preventing AMR in patients who are sensitized to their donor, while Cohort B focuses on treating patients with active AMR.Participants in …
