This study investigates the effects of an investigational medication on people with moderate to severe ulcerative colitis (UC). Ulcerative colitis is a condition where the lining of the large intestine becomes inflamed and develops sores. The study will compare different doses of the investigational medication to a placebo, which is …
This study investigates the effects of an investigational medication compared to an existing treatment in people with relapsing forms of multiple sclerosis, a condition where the immune system mistakenly attacks the protective covering of the nerves, causing communication problems between the brain and the rest of the body. The study …
This study investigates the efficacy and safety of an investigational medication in delaying disability progression in individuals with non-relapsing secondary progressive multiple sclerosis (nrSPMS). nrSPMS is a stage of multiple sclerosis (MS) where symptoms worsen over time without periods of remission. Participants will be randomly assigned to receive either the …
This study investigates the treatment of newly diagnosed moderate or severe chronic graft-versus-host disease (cGVHD). Chronic GVHD is a condition that can occur after a stem cell or bone marrow transplant, where the donated cells attack the recipient's body. The study aims to assess the effectiveness of an investigational medication …
This study investigates the effectiveness and safety of an investigational medication compared to a placebo in adults with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) who do not respond to available treatments. CIDP is a condition where the body's immune system mistakenly attacks the protective covering of the nerves, leading to weakness …
This study investigates the effectiveness and safety of an investigational medication compared to intravenous immunoglobulin (IVIg) in adults with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). CIDP is a neurological disorder that causes weakness and sensory loss due to inflammation of the peripheral nerves. The purpose of this study is to assess …
This study investigates an investigational medication for the treatment of asthma. Asthma is a condition where the airways in the lungs become inflamed and narrow, making it hard to breathe. The purpose of this study is to assess how effective and safe the investigational medication is when added to the …
This study investigates the effects of an investigational medication compared to a placebo in adults with moderate to severe hidradenitis suppurativa (HS). HS is a chronic skin condition that causes small, painful lumps under the skin. These lumps can break open or form tunnels under the skin. The study involves …
This study investigates the efficacy and safety of an investigational medication compared to a placebo in patients who have undergone a bilateral lung transplant and have chronic lung allograft dysfunction (CLAD). CLAD is a condition where the lung function declines over time after a transplant. Participants must be at least …
This study investigates a meningococcal vaccine in children under 10 years old. Meningococcal disease is a serious illness caused by bacteria that can lead to infections in the brain and spinal cord. The purpose of this study is to compare two formulations of a new investigational vaccine with existing vaccines. …
