This study investigates the effects of an investigational medication on pruritus, which is a severe itching sensation, in individuals with Lichen Simplex Chronicus (LSC). LSC is a skin condition characterized by thickened, itchy patches of skin. The study compares the investigational medication given through subcutaneous injections to placebo injections in …
This study investigates the effectiveness of an investigational medication compared to a placebo in treating pruritus, or severe itching, in adults with Lichen Simplex Chronicus (LSC). LSC is a skin condition characterized by thickened, itchy patches of skin. The purpose of this study is to see if the investigational medication …
This study investigates the effects of an investigational medication on people with chronic rhinosinusitis with nasal polyps (CRSwNP). CRSwNP is a condition where the lining of the nasal passages and sinuses becomes swollen, leading to the growth of polyps. The study will compare two different dosing regimens of the investigational …
This study investigates the safety and effectiveness of an investigational medication in people with moderate to severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes red, itchy, and inflamed skin. Participants in this study have previously been treated with the investigational medication in earlier trials. The study …
This study investigates the long-term safety and how well an investigational medication works in people with moderate to severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes itchy and inflamed skin. The study is for participants who are 12 years or older.Participants will receive the investigational medication …
This study investigates the safety and effectiveness of an investigational medication in children aged 2 to under 6 years who have uncontrolled asthma or experience frequent severe wheezing. Uncontrolled asthma means that the usual treatments are not enough to manage the symptoms. The study is divided into two parts. Part …
This study investigates the long-term safety and tolerability of an investigational medication in adults with different types of multiple sclerosis (MS), such as relapsing MS (RMS), primary progressive MS (PPMS), and non-relapsing secondary progressive MS (NRSPMS). Multiple sclerosis is a condition where the immune system mistakenly attacks the protective covering …
The purpose of this study is to investigate the effectiveness of an investigational medication for individuals with moderate-to-severe atopic dermatitis, a skin condition that causes itchy and inflamed skin. This study is designed for participants who have previously responded to a specific treatment in earlier studies and will examine if …
This study investigates the effects of investigational medications on primary focal segmental glomerulosclerosis (FSGS) and primary minimal change disease (MCD). FSGS and MCD are kidney disorders that cause proteinuria, which is an excess of protein in the urine. The purpose of this study is to see how these investigational medications …
This study investigates the effects of an investigational medication on adults with moderate-to-severe ulcerative colitis (UC). Ulcerative colitis is a long-term condition that causes inflammation and sores in the digestive tract, particularly affecting the lining of the large intestine and rectum. The purpose of this study is to evaluate how …
