This study investigates the safety and immune response of an investigational vaccine for meningococcal disease in children under 10 years old. The purpose of this study is to evaluate two formulations of the investigational vaccine, comparing them to existing vaccines. The study is conducted in three stages: Stage 1 involves …
This study investigates the improvement of itching in individuals with Lichen Simplex Chronicus (LSC) using subcutaneous injections of an investigational medication compared to placebo. The study involves male and female participants who are 18 years or older and have moderate-to-severe LSC.Participants in the study will receive either the investigational medication …
This study investigates the effect of an investigational medication on reducing itchiness in individuals with Lichen Simplex Chronicus (LSC). The purpose of this study is to compare the effectiveness of the investigational medication given by injection to a placebo in adults aged 18 and over who have moderate-to-severe LSC.Participants will …
This study investigates the effects of an investigational medication on individuals with chronic rhinosinusitis with nasal polyps (CRSwNP). The purpose of this study is to assess the efficacy, safety, and tolerability of two dosing regimens of the investigational medication compared to a placebo, alongside intranasal corticosteroids (INCS).Participants will be randomly …
This study investigates the efficacy and safety of an investigational medication in adults with moderate to severe Ulcerative Colitis. The study compares different doses of the investigational medication to a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.Participants will be …
This study investigates an investigational medication for adults with moderate to severe ulcerative colitis (UC). The purpose of this study is to evaluate the effectiveness and safety of the investigational medication compared to a placebo. Participants will be divided into four study arms, with three different doses of the investigational …
This study investigates the long-term safety and effectiveness of an investigational medication in individuals with moderate to severe atopic dermatitis. The study includes participants who have previously taken part in trials for the investigational medication and focuses on understanding its effects over an extended period.Participants will attend visits every four …
This study investigates the safety and efficacy of an investigational medication for individuals aged 12 and older with moderate to severe atopic dermatitis. The study aims to understand how this medication affects participants over a long-term period.Participants will receive the investigational medication through injections under the skin. This open-label study …
This study investigates the efficacy and safety of an investigational medication in adults with nonrelapsing secondary progressive multiple sclerosis (nrSPMS). The purpose of this study is to determine whether the investigational medication can delay disability progression compared to a placebo.Participants in this randomized, double-blind, placebo-controlled study will receive either the …
This study investigates the effects of an investigational medication on children aged 2 to less than 6 years with uncontrolled asthma or recurrent severe asthmatic wheeze. The study aims to evaluate the safety and effectiveness of the investigational medication compared to a placebo, which is an inactive substance that looks …