This study investigates the efficacy and safety of an investigational therapy compared to a placebo in adults aged 18 and older with moderately to severely active ulcerative colitis. Participants in this study have an eosinophilic phenotype, meaning they have higher levels of eosinophils, a type of white blood cell, in …
This study investigates the effects of an investigational medication compared to a daily oral dose of another treatment in adults with relapsing forms of multiple sclerosis (RMS). This study aims to measure the annualized relapse rate (ARR) in participants aged 18 to 55 who have been diagnosed with RMS.Participants will …
This study investigates the effects of an investigational medication compared with a placebo in adults with high-risk asthma. This study involves adults aged 18 to 80 years who have asthma but are not eligible for biologic treatments.Participants will receive either the investigational medication or a placebo, which is an inactive …
This study investigates the impact of an investigational medication compared to standard care on lung function in adults with uncontrolled moderate to severe asthma. This study aims to determine if the investigational medication can prevent or slow down the decline in lung function.Participants in the study will be randomly assigned …
This study investigates the safety and efficacy of an investigational medication for individuals aged 12 and older with moderate to severe atopic dermatitis. The study aims to understand how this medication affects participants over a long-term period.Participants will receive the investigational medication through injections under the skin. This open-label study …
This study investigates the long-term safety and tolerability of an investigational medication in adults with multiple sclerosis (MS). Participants in this study have previously been part of earlier trials of the investigational medication.Participants will continue or start open-label treatment with the investigational medication, depending on their previous study involvement. Some …
This study investigates the treatment response and safety of two dose regimens of an investigational medication compared with treatment withdrawal in individuals aged 12 years and older with moderate-to-severe atopic dermatitis. The study aims to see if participants who responded to the investigational medication in earlier studies can maintain their …
This study investigates the long-term safety and efficacy of an investigational medication in adult participants with asthma. Participants who have completed previous studies with the investigational medication are eligible to join this extended study.Participants will receive the investigational medication and continue their background therapy, which may include inhaled corticosteroids and …
This study investigates the clinical outcomes of patients with Gaucher disease through an observational registry. The purpose of the registry is to gather data on how the disease progresses and affects patients over time, without altering their treatment plans. This helps in understanding the natural history of the disease and …