This study investigates the use of an investigational gene therapy for adults with phenylketonuria (PKU), a condition where the body cannot break down an amino acid called phenylalanine (Phe). The purpose of this study is to see if the investigational treatment can safely reduce Phe levels and allow participants to …
This study investigates a treatment for chronic rhinosinusitis with nasal polyps (CRSwNP), a condition where growths called polyps form in the nasal passages and sinuses, causing congestion and other symptoms. The purpose of this study is to evaluate the effectiveness and safety of an investigational medication given as an injection …
This study investigates the effects of an investigational medication compared to a placebo in adults aged 18 to 70 with active Systemic Lupus Erythematosus (SLE). SLE is a chronic autoimmune disease where the immune system attacks healthy tissues, causing inflammation and damage in various body parts. Participants will be randomly …
This study investigates the effects of an investigational medication on people with moderate to severe ulcerative colitis (UC). Ulcerative colitis is a condition where the lining of the large intestine becomes inflamed and develops sores. The study will compare different doses of the investigational medication to a placebo, which is …
This study investigates the effects of an investigational medication compared to an existing treatment in people with relapsing forms of multiple sclerosis, a condition where the immune system mistakenly attacks the protective covering of the nerves, causing communication problems between the brain and the rest of the body. The study …
This study investigates the effects of an investigational treatment for people with moderate to severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes red, itchy, and inflamed skin. The study compares the investigational treatment to a placebo, which is an inactive substance that looks the same but …
This study investigates the efficacy and safety of an investigational medication in delaying disability progression in individuals with non-relapsing secondary progressive multiple sclerosis (nrSPMS). nrSPMS is a stage of multiple sclerosis (MS) where symptoms worsen over time without periods of remission. Participants will be randomly assigned to receive either the …
An investigational medication is what is being studied to see if symptoms improve while taking it. It is not yet approved for general use by regulatory authorities. This study uses an investigational medication called Riliprubart. The investigational medicine is injected in a vein or under the skin, either at the …
This study investigates chronic graft versus host disease (cGVHD), a condition where transplanted donor cells attack the recipient's body after a stem cell or bone marrow transplant. The purpose of this study is to find out if adding the investigational medication to the usual treatment with corticosteroids is more effective. …
This study investigates the treatment of moderate-to-severe atopic dermatitis (AD), a skin condition causing itchy and inflamed skin, in individuals who have not responded well to topical treatments. The purpose of this study is to compare the safety and effectiveness of an investigational medication given by injection to a placebo, …
