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Found 3 Chronic Obstructive Pulmonary Disease (COPD) trials

Below is a list of actively recruiting clinical trials based on your search for "Chronic Obstructive Pulmonary Disease (COPD)"

Study to Assess the Efficacy, Safety, and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD) (AERIFY-2)

40-85 years
All genders
Phase 3
Interventional
Primary Objective: Primary population (former smokers cohort): Evaluate the efficacy of itepekimab compared with placebo on the annualized rate of acute moderate-or-severe COPD exacerbations in former smokers with moderate-to-severe COPD Secondary Objectives: Primary population (former smokers cohort): Evaluate the efficacy of itepekimab compared with placebo on pulmonary function in former …
About the study

A Study to Investigate Long-term Safety and Tolerability of Itepekimab in Participants With COPD

40-85 years
All genders
Phase 3
Interventional
This is a parallel, double blind, Phase 3, 2-arm study that is designed to provide additional safety information, assess the durability of treatment response, and provide additional PK and immunogenicity assessments. The primary purpose of this study is to evaluate safety and tolerability of both itepekimab SC Q2W or itepekimab …
About the study

Mechanistic Study of the Effect of Itepekimab on Airway Inflammation in Patients With COPD

40-70 years
All genders
Phase 2
Interventional
This study is an exploratory, two-part, 12-week, Phase 2a study to evaluate the mechanism of action of Itepekimab (anti-IL-33-mAb) and its impact on airway inflammation in former and current smokers with COPD, aged 40 to 70 years. This study consists of participants who have been on a standard-of-care (SoC) mono …
About the study