This study investigates the effects of an investigational medication on adults with non-responsive celiac disease (NRCD) who are on a gluten-free diet. Celiac disease is a condition where eating gluten leads to damage in the small intestine. The study aims to see how the investigational medication affects the small intestine's …
This study investigates the efficacy and safety of an investigational medication in delaying disability progression in individuals with non-relapsing secondary progressive multiple sclerosis (nrSPMS). nrSPMS is a stage of multiple sclerosis (MS) where symptoms worsen over time without periods of remission. Participants will be randomly assigned to receive either the …
This study investigates the treatment of newly diagnosed moderate or severe chronic graft-versus-host disease (cGVHD). Chronic GVHD is a condition that can occur after a stem cell or bone marrow transplant, where the donated cells attack the recipient's body. The study aims to assess the effectiveness of an investigational medication …
This study investigates the effectiveness and safety of an investigational medication compared to a placebo in adults with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) who do not respond to available treatments. CIDP is a condition where the body's immune system mistakenly attacks the protective covering of the nerves, leading to weakness …
This study investigates the effectiveness and safety of an investigational medication compared to intravenous immunoglobulin (IVIg) in adults with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). CIDP is a neurological disorder that causes weakness and sensory loss due to inflammation of the peripheral nerves. The purpose of this study is to assess …
This study investigates an investigational medication for the treatment of asthma. Asthma is a condition where the airways in the lungs become inflamed and narrow, making it hard to breathe. The purpose of this study is to assess how effective and safe the investigational medication is when added to the …
This study investigates the safety and efficacy of three different dose levels of an investigational medication compared to a placebo in people with newly diagnosed Type 1 Diabetes (T1D) who are on insulin treatment. Type 1 diabetes is a chronic disease where the body's defense system mistakenly attacks specific cells …
This study investigates the long-term safety and tolerability of an investigational medication in adults with different types of multiple sclerosis (MS), such as relapsing MS (RMS), primary progressive MS (PPMS), and non-relapsing secondary progressive MS (NRSPMS). Multiple sclerosis is a condition where the immune system mistakenly attacks the protective covering …
The purpose of this study is to investigate the effectiveness of an investigational medication for individuals with moderate-to-severe atopic dermatitis, a skin condition that causes itchy and inflamed skin. This study is designed for participants who have previously responded to a specific treatment in earlier studies and will examine if …
This study investigates the long-term safety and effects of an investigational medication in adults with Alpha-1 Antitrypsin Deficiency (AATD) emphysema. AATD is a genetic condition that can lead to lung diseases like emphysema. Emphysema is a lung condition that causes shortness of breath due to damaged air sacs in the …
