This study investigates the effects of an investigational medication on people with moderate to severe ulcerative colitis (UC). Ulcerative colitis is a condition where the lining of the large intestine becomes inflamed and develops sores. The study will compare different doses of the investigational medication to a placebo, which is …
This study investigates the effects of an investigational medication compared to an existing treatment in people with relapsing forms of multiple sclerosis, a condition where the immune system mistakenly attacks the protective covering of the nerves, causing communication problems between the brain and the rest of the body. The study …
This study investigates the efficacy and safety of an investigational medication in delaying disability progression in individuals with non-relapsing secondary progressive multiple sclerosis (nrSPMS). nrSPMS is a stage of multiple sclerosis (MS) where symptoms worsen over time without periods of remission. Participants will be randomly assigned to receive either the …
This study investigates an investigational medication for adults with moderate to severe Crohn's Disease, a condition that causes inflammation in the digestive tract, leading to symptoms like abdominal pain and diarrhea. The purpose of this study is to compare the effectiveness of different doses of the investigational medication to a …
This study investigates the effect of an investigational medication compared to a placebo in people with recently diagnosed Type 1 diabetes who are on insulin therapy. Type 1 diabetes is a chronic disease where the body's defense system mistakenly attacks specific cells within the pancreas, which make insulin. Insulin helps …
This study investigates the safety and immune response of an investigational pneumococcal conjugate vaccine in infants. Pneumococcal vaccines are designed to protect against infections caused by the bacteria Streptococcus pneumoniae. The study aims to determine how well the investigational vaccine works in creating antibodies, which are proteins that help fight …
This study investigates the effects of an investigational medication for people with chronic rhinosinusitis with nasal polyps (CRSwNP). CRSwNP is a condition where the tissue inside the nose becomes swollen and forms small growths called polyps. The study compares two different doses of the investigational medication to a placebo, which …
This study investigates the effects of an investigational monoclonal antibody on respiratory syncytial virus (RSV) in children. RSV is a common virus that affects the respiratory tract, particularly in young children. This study focuses on neonates and infants up to 12 months old during their first RSV season, as well …
This study investigates the effect of an investigational medication compared to standard care in preventing or slowing the decline of lung function in adults with uncontrolled moderate to severe asthma. Asthma is a condition where the airways in the lungs become inflamed and narrow, making it hard to breathe. The …
This study investigates the long-term safety and how well an investigational medication works in people with moderate to severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes itchy and inflamed skin. The study is for participants who are 12 years or older.Participants will receive the investigational medication …
