This study investigates the effects of an investigational medication on adults with non-responsive celiac disease (NRCD) who are on a gluten-free diet. Celiac disease is a condition where eating gluten leads to damage in the small intestine. The study aims to see how the investigational medication affects the small intestine's …
This study investigates an investigational medication for adults with moderate to severe Crohn's Disease, a condition that causes inflammation in the digestive tract, leading to symptoms like abdominal pain and diarrhea. The purpose of this study is to compare the effectiveness of different doses of the investigational medication to a …
This study investigates an investigational medication for the treatment of asthma. Asthma is a condition where the airways in the lungs become inflamed and narrow, making it hard to breathe. The purpose of this study is to assess how effective and safe the investigational medication is when added to the …
This study investigates the effects of an investigational medication for people with moderate-to-severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes itchy, inflamed skin. The study focuses on participants aged 12 years and older who have not responded well to previous treatments, including biologic medications or oral …
This study investigates the effect of an investigational medication compared to a placebo in people with recently diagnosed Type 1 diabetes who are on insulin therapy. Type 1 diabetes is a chronic disease where the body's defense system mistakenly attacks specific cells within the pancreas, which make insulin. Insulin helps …
This study investigates the efficacy and safety of an investigational medication compared to a placebo in patients who have undergone a bilateral lung transplant and have chronic lung allograft dysfunction (CLAD). CLAD is a condition where the lung function declines over time after a transplant. Participants must be at least …
This study investigates the safety and ability of an investigational pneumococcal vaccine to stimulate the body's defense system in infants. The study compares this investigational vaccine with a licensed pneumococcal vaccine when given alongside routine vaccines to infants aged about 2 months. The investigational vaccine is being tested to see …
This study investigates the effects of an investigational medication on people with chronic rhinosinusitis with nasal polyps (CRSwNP). CRSwNP is a condition where the lining of the nasal passages and sinuses becomes swollen, leading to the growth of polyps. The study will compare two different dosing regimens of the investigational …
This study investigates the use of an investigational medication in combination with other agents to treat individuals with relapsed or refractory myeloma. Myeloma is a type of cancer that affects plasma cells in the bone marrow, leading to issues such as bone pain, anemia, and infections. The study includes multiple …
This study investigates the effectiveness and safety of an investigational medication in treating adults with Chronic Pruritus of Unknown Origin (CPUO). Pruritus is a medical term for severe itching. The study includes two parts, Study A and Study B, involving male and female participants aged 18 to 90 years. Participants …
