This study investigates the efficacy and safety of an investigational medication in adults with moderate-to-severe ulcerative colitis. Participants will be in the study for up to 59 weeks, including a 28-day screening period, a 52-week main treatment period, and a 2-week follow-up. The main treatment period consists of a 12-week …
This study investigates the effects of an investigational medication on adults with moderate to severe Crohn's Disease. The purpose is to evaluate the safety and effectiveness of different doses compared to a placebo. Participants will be in the study for up to 59 weeks, including a 4-week screening period, 52 …
This study investigates the safety and activity of an investigational medication in patients with relapsed or refractory B-cell Non-Hodgkin Lymphoma (B-NHL). This study aims to find the best dose by examining safety, how the drug moves through the body (pharmacokinetics), how it affects the body (pharmacodynamics), its clinical activity, and …
This study investigates the effectiveness and safety of an investigational medication in treating adults with moderate to severe Ulcerative Colitis. The study will compare different doses of the investigational medication to a placebo to see which works best.Participants will be randomly assigned to one of three study arms. They will …
This study investigates the effectiveness and safety of an investigational medication compared to a placebo for treating chronic lung allograft dysfunction (CLAD) in adults. Participants will have already undergone a bilateral lung transplant and will be receiving a standard treatment regimen including azithromycin and immunosuppression therapies.Participants in the study will …
This study investigates the efficacy, safety, and tolerability of an investigational medication in participants with chronic rhinosinusitis with nasal polyps (CRSwNP). The study aims to compare two dosing regimens of the investigational medication with a placebo, in addition to standard treatment with intranasal corticosteroids.Participants will undergo a series of procedures …
This study investigates the treatment of moderate to severe hidradenitis suppurativa. Participants will be involved in the study for up to 60 weeks if they do not continue into the long-term extension study, or up to 52 weeks if they do. The purpose of this study is to assess the …
This study investigates the use of an investigational medication in combination with other novel agents in participants with relapsed or refractory multiple myeloma (RRMM). The study includes several substudies with different combinations of treatments, some with and some without the drug dexamethasone.Participants in this study will undergo various procedures depending …
This study investigates the safety and efficacy of an investigational medication injected under the skin in adult participants with relapsed or refractory multiple myeloma. This study aims to determine the best dose of the investigational medication for future research.Participants will be involved in two parts of the study. In Part …
This study investigates the efficacy and safety of an investigational medication in patients with moderate to severe Crohn's disease. The study aims to compare different doses of the investigational medication with a placebo, which is an inactive substance that looks like the investigational medication but does not contain any medicine.Participants …
