This study investigates the effect of an investigational medication compared to standard care in preventing or slowing the decline of lung function in adults with uncontrolled moderate to severe asthma. Asthma is a condition where the airways in the lungs become inflamed and narrow, making it hard to breathe. The …
This study investigates the long-term safety and how well an investigational medication works in people with moderate to severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that causes itchy and inflamed skin. The study is for participants who are 12 years or older.Participants will receive the investigational medication …
This study investigates the safety and effectiveness of an investigational medication in children aged 2 to under 6 years who have uncontrolled asthma or experience frequent severe wheezing. Uncontrolled asthma means that the usual treatments are not enough to manage the symptoms. The study is divided into two parts. Part …
This study investigates the effects of investigational medications on primary focal segmental glomerulosclerosis (FSGS) and primary minimal change disease (MCD). FSGS and MCD are kidney disorders that cause proteinuria, which is an excess of protein in the urine. The purpose of this study is to see how these investigational medications …
This study investigates an investigational medication for adults with moderate to severe Crohn's Disease, a condition that causes inflammation in the digestive tract, leading to symptoms like abdominal pain and diarrhea. The purpose of this study is to compare the effectiveness of different doses of the investigational medication to a …
This study investigates the clinical outcomes of patients with Gaucher disease, a genetic disorder where fatty substances build up in certain organs, particularly the spleen and liver. The study is observational, meaning it does not involve any experimental treatments. Instead, it aims to understand the variability, progression, and natural history …
This study investigates the outcomes of patients with Mucopolysaccharidosis I (MPS I), a rare genetic disorder. MPS I is a condition where the body cannot properly break down certain sugar molecules, leading to various health problems. The purpose of this study is to collect data to understand the natural history …
This study investigates Pompe disease, a rare genetic disorder that affects the body's ability to break down a complex sugar called glycogen. The purpose of this study is to understand how Pompe disease progresses over time and how it varies among patients. This includes looking at patients who receive treatment …
This study investigates Fabry disease, a rare genetic condition that affects the body's ability to break down a specific type of fat. The purpose of this study is to track the health outcomes of people with Fabry disease over time, regardless of the treatment they receive. The study includes both …
This study investigates pediatric patients with moderate to severe atopic dermatitis (AD), a skin condition causing red, itchy, and inflamed skin. The purpose is to understand the characteristics of these patients, especially when their condition is not well-managed with topical treatments, or when such treatments are not suitable.Participants will be …
