The purpose of this study is to investigate the effects of an investigational medication in people with chronic rhinosinusitis with nasal polyps (CRSwNP). The study focuses on evaluating the safety and effectiveness of the investigational medication when added to standard nasal treatments. Researchers aim to understand how well the medication …
This study investigates relapsing forms of multiple sclerosis. The purpose of this study is to measure the annualized relapse rate in adults with this condition.The study will focus on evaluating the safety and effectiveness of an investigational medication compared to an existing treatment. It aims to provide insights into how …
This study investigates the treatment of moderate-to-severe atopic dermatitis (AD) in participants aged 12 years and older. The purpose is to evaluate the effects of a subcutaneous treatment for those who have not responded well to previous biologic therapies or oral JAK inhibitors.The study will focus on assessing the safety …
This study investigates the treatment of primary focal segmental glomerulosclerosis (FSGS) and primary minimal change disease (MCD). The study focuses on evaluating the effectiveness and safety of investigational medications compared to a placebo, specifically looking at changes in protein levels in urine and remission rates of nephrotic syndrome.Who can participate: …
This study investigates the long-term safety and efficacy of an investigational medication in adults with asthma. It is an extension of previous studies and will last up to 100 weeks, with participants receiving treatment for up to 96 weeks. The purpose of this study is to continue monitoring the effects …
This study investigates the safety and efficacy of an investigational medication in people with sickle-cell disease (SCD). The focus of the study is to evaluate how well the investigational medication works and how safe it is for participants with SCD. Researchers aim to gather information that could help improve understanding …
This study investigates chronic obstructive pulmonary disease (COPD) that is inadequately controlled and characterized by an eosinophilic phenotype. The study focuses on adult participants aged 40 to 80 years.The study aims to assess the safety, effectiveness, and tolerability of an investigational medication given through injections compared to a placebo. The …
This study investigates the condition known as chronic obstructive pulmonary disease (COPD) characterized by an eosinophilic phenotype. The purpose of this study is to understand how an investigational medication compares to a placebo in adult participants who have COPD that is not well controlled.The study focuses on evaluating the efficacy, …
This study investigates the clinical outcomes of patients with Gaucher disease. The study is observational, meaning it collects data from patients receiving routine care without altering their treatment. It aims to enhance understanding of the disease's variability, progression, and natural history to aid in better therapeutic interventions.Participants will undergo clinical …
This study investigates Pompe disease, focusing on muscle function impacts due to glycogen buildup. The purpose of this observational study is to track the natural history and outcomes of Pompe disease in patients worldwide, regardless of treatment status. An observational study involves collecting data by observing participants receiving routine care, …
