This study investigates the effects of an investigational medication in people with chronic rhinosinusitis with nasal polyps (CRSwNP). The purpose of this study is to evaluate how well the investigational medication works, how safe it is, and how well people tolerate it when added to standard treatment with intranasal corticosteroids.Participants …
This study investigates the effects of an investigational medication on individuals with chronic rhinosinusitis with nasal polyps (CRSwNP). The purpose of this study is to assess the efficacy, safety, and tolerability of two dosing regimens of the investigational medication compared to a placebo, alongside intranasal corticosteroids (INCS).Participants will be randomly …
This study investigates the impact of an investigational medication compared to standard care on lung function in adults with uncontrolled moderate to severe asthma. This study aims to determine if the investigational medication can prevent or slow down the decline in lung function.Participants in the study will be randomly assigned …
This study investigates the long-term safety and effectiveness of an investigational medication in individuals with moderate to severe atopic dermatitis. The study includes participants who have previously taken part in trials for the investigational medication and focuses on understanding its effects over an extended period.Participants will attend visits every four …
This study investigates the safety and efficacy of an investigational medication for individuals aged 12 and older with moderate to severe atopic dermatitis. The study aims to understand how this medication affects participants over a long-term period.Participants will receive the investigational medication through injections under the skin. This open-label study …
This study investigates the efficacy and safety of an investigational medication in adults with nonrelapsing secondary progressive multiple sclerosis (nrSPMS). The purpose of this study is to determine whether the investigational medication can delay disability progression compared to a placebo.Participants in this randomized, double-blind, placebo-controlled study will receive either the …
This study investigates the effects of an investigational medication on children aged 2 to less than 6 years with uncontrolled asthma or recurrent severe asthmatic wheeze. The study aims to evaluate the safety and effectiveness of the investigational medication compared to a placebo, which is an inactive substance that looks …
This study investigates the efficacy and safety of an investigational medication given as a subcutaneous injection for individuals aged 12 years and older with moderate-to-severe atopic dermatitis (AD). The study focuses on participants who have not responded adequately to prior biologic therapies or oral JAK inhibitors, while continuing their topical …
This study investigates the long-term safety and tolerability of an investigational medication in adults with multiple sclerosis (MS). Participants in this study have previously been part of earlier trials of the investigational medication.Participants will continue or start open-label treatment with the investigational medication, depending on their previous study involvement. Some …
This study investigates the effectiveness and safety of three investigational medications compared to a placebo in treating primary focal segmental glomerulosclerosis (FSGS) or primary minimal change disease (MCD). These kidney disorders can lead to nephrotic syndrome, characterized by high levels of protein in the urine (proteinuria). The purpose of this …
