This study investigates the treatment of moderate to severe atopic dermatitis (AD), a skin condition characterized by red, itchy, and inflamed skin. The purpose of this study is to evaluate the effectiveness and safety of an investigational medication administered through subcutaneous injection compared to a placebo in individuals aged 12 …
This study investigates the effectiveness of an investigational medication in slowing down the progression of disability in individuals with non-relapsing Secondary Progressive Multiple Sclerosis (nrSPMS). Secondary Progressive Multiple Sclerosis (SPMS) is a stage of multiple sclerosis where the disease worsens over time, with or without relapses. Participants in this study …
This study investigates the effects of an investigational medication given as subcutaneous injections for adults with severe alopecia areata (AA). Alopecia areata is a condition where people lose hair from some or all areas of the body, often from the scalp. The study will compare the investigational medication to a …
This study investigates the treatment of newly diagnosed moderate or severe chronic graft-versus-host disease (cGVHD). Chronic GVHD is a condition that can occur after a stem cell or bone marrow transplant, where the donated cells attack the recipient's body. The study aims to understand how well the investigational medication works …
This study investigates the effects of an investigational medication combined with other treatments for people with relapsed or refractory myeloma. Myeloma is a type of cancer that affects plasma cells in the bone marrow. The study includes several substudies, each testing different combinations of treatments to see how well they …
This study investigates the efficacy and safety of an investigational medication compared to a placebo in patients who have undergone a bilateral lung transplant. The condition being studied is chronic lung allograft dysfunction (CLAD), which is a progressive condition affecting lung function after a transplant. Participants will receive either the …
This study investigates an investigational medication for patients with relapsed or refractory multiple myeloma (RRMM). Multiple myeloma is a type of cancer that affects plasma cells, which are a kind of white blood cell found in the bone marrow. The study is divided into two parts: dose escalation and dose …
This study investigates the safety and effects of an investigational medication in people with HER2+ tumors. HER2+ tumors are a type of cancer that have high levels of a protein called human epidermal growth factor receptor 2, which can promote the growth of cancer cells. The study will look at …
This study investigates the safety and effects of an investigational medication in people with certain blood cancers, such as acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Blood cancers affect the blood, bone marrow, and lymph nodes. The study aims to understand how the investigational medication works in the body …
This study investigates the long-term safety of an investigational medication for individuals with multiple myeloma. Multiple myeloma is a type of cancer that affects plasma cells, which are a kind of white blood cell found in bone marrow. The purpose of this study is to provide continued access to the …
