The purpose of this study is to investigate the effectiveness of an investigational medication for individuals with moderate-to-severe atopic dermatitis, a skin condition that causes itchy and inflamed skin. This study is designed for participants who have previously responded to a specific treatment in earlier studies and will examine if …
This study investigates the long-term safety and effects of an investigational medication in adults with Alpha-1 Antitrypsin Deficiency (AATD) emphysema. AATD is a genetic condition that can lead to lung diseases like emphysema. Emphysema is a lung condition that causes shortness of breath due to damaged air sacs in the …
This study investigates the effects of investigational medications on primary focal segmental glomerulosclerosis (FSGS) and primary minimal change disease (MCD). FSGS and MCD are kidney disorders that cause proteinuria, which is an excess of protein in the urine. The purpose of this study is to see how these investigational medications …
This study investigates the effects of an investigational medication in patients with relapsed or refractory multiple myeloma (RRMM). Multiple myeloma is a type of cancer that affects plasma cells, which are a kind of white blood cell in the bone marrow. The purpose of the study is to find the …
This study investigates an investigational medication for adults with moderate to severe Crohn's Disease, a condition that causes inflammation in the digestive tract, leading to symptoms like abdominal pain and diarrhea. The purpose of this study is to compare the effectiveness of different doses of the investigational medication to a …
This study investigates the effects of an investigational medication on adults with moderate-to-severe ulcerative colitis (UC). Ulcerative colitis is a long-term condition that causes inflammation and sores in the digestive tract, particularly affecting the lining of the large intestine and rectum. The purpose of this study is to evaluate how …
This study investigates the effect of an investigational medication compared to a placebo in people with recently diagnosed Type 1 diabetes who are on insulin therapy. Type 1 diabetes is a chronic disease where the body's defense system mistakenly attacks specific cells within the pancreas, which make insulin. Insulin helps …
This study investigates the effects of an investigational medication on prostate cancer, a disease where cancer cells form in the tissues of the prostate. The purpose of this study is to understand how the investigational medication works as a single agent and in combination with other treatments. The study will …
This study investigates the safety and immune response of different investigational vaccines for respiratory viruses. The vaccines include formulations for trivalent influenza and a combined vaccine for respiratory syncytial virus, human metapneumovirus, and parainfluenza virus type 3. A lipid nanoparticle is used in the vaccines to help deliver the vaccine …
This study investigates the clinical outcomes of patients with Gaucher disease, a genetic disorder where fatty substances build up in certain organs, particularly the spleen and liver. The study is observational, meaning it does not involve any experimental treatments. Instead, it aims to understand the variability, progression, and natural history …
