This study investigates the safety and efficacy of an investigational medication for individuals aged 12 and older with moderate to severe atopic dermatitis. The study aims to understand how this medication affects participants over a long-term period.Participants will receive the investigational medication through injections under the skin. This open-label study …
This study investigates the efficacy and safety of an investigational medication in adults with nonrelapsing secondary progressive multiple sclerosis (nrSPMS). The purpose of this study is to determine whether the investigational medication can delay disability progression compared to a placebo.Participants in this randomized, double-blind, placebo-controlled study will receive either the …
This study investigates the efficacy and safety of an investigational medication given as a subcutaneous injection for individuals aged 12 years and older with moderate-to-severe atopic dermatitis (AD). The study focuses on participants who have not responded adequately to prior biologic therapies or oral JAK inhibitors, while continuing their topical …
This study investigates the treatment response and safety of two dose regimens of an investigational medication compared with treatment withdrawal in individuals aged 12 years and older with moderate-to-severe atopic dermatitis. The study aims to see if participants who responded to the investigational medication in earlier studies can maintain their …
This study investigates the effectiveness and safety of three investigational medications compared to a placebo in treating primary focal segmental glomerulosclerosis (FSGS) or primary minimal change disease (MCD). These kidney disorders can lead to nephrotic syndrome, characterized by high levels of protein in the urine (proteinuria). The purpose of this …
This study investigates the safety and efficacy of an investigational medication injected under the skin in adult participants with relapsed or refractory multiple myeloma. This study aims to determine the best dose of the investigational medication for future research.Participants will be involved in two parts of the study. In Part …
This study investigates the efficacy and safety of an investigational medication in patients with moderate to severe Crohn's disease. The study involves different doses of the investigational medication compared to a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.Participants will …
This study investigates the effects of an investigational medication compared to a placebo in adults with chronic obstructive pulmonary disease (COPD) that is not well controlled and is characterized by a higher number of eosinophils, a type of white blood cell. The purpose of this study is to assess how …
This study investigates an investigational medication for metastatic castration resistant prostate cancer (mCRPC). The purpose of this study is to understand the safety, how the body processes the investigational medication, and its preliminary effectiveness in treating mCRPC.Participants in the study will receive the investigational medication in different parts. Initially, there …
This study investigates the clinical outcomes of patients with Gaucher disease through an observational registry. The purpose of the registry is to gather data on how the disease progresses and affects patients over time, without altering their treatment plans. This helps in understanding the natural history of the disease and …
