This study investigates the treatment of primary focal segmental glomerulosclerosis (FSGS) and primary minimal change disease (MCD) in participants aged 16 to 75 years. These conditions affect the kidneys and can lead to nephrotic syndrome, which is characterized by high levels of protein in the urine.The focus of the study …
This study investigates the safety and effectiveness of an investigational medication for adults with relapsed or refractory myeloma. The research aims to understand how well the medication works and how safe it is for people who have tried other treatments without success.The study focuses on evaluating the investigational medication's effects …
This study investigates the safety and efficacy of an investigational gene therapy for individuals with non-congenital myotonic dystrophy type 1 (DM1). The purpose of this study is to assess how well the investigational therapy can reduce levels of a specific protein linked to DM1 and improve muscle function in participants …
This study investigates the safety, efficacy, and immunogenicity of an investigational vaccine for Chlamydia in adults aged 18 to 29 years. The study aims to test different dose levels of the vaccine to see how well it works and how safe it is.The purpose of this study is to understand …
This study investigates the condition of Crohn's disease and aims to evaluate the effectiveness and safety of an investigational medication. The focus of this study is to assess how different doses of the investigational medication work in comparison to a placebo in individuals with moderate to severe Crohn's disease. The …
This study investigates the effectiveness, safety, and tolerability of an investigational medication in adults with chronic obstructive pulmonary disease (COPD) that is not well controlled and is characterized by an eosinophilic phenotype.The focus of this study is to evaluate how the investigational medication compares to a placebo in terms of …
This study investigates the efficacy and safety of an investigational medication compared to another treatment in adults undergoing kidney transplantation. The purpose is to understand how well the investigational medication works and its safety profile for people receiving their first kidney transplant.The focus of the study is to evaluate how …
This study investigates the safety and activity of an investigational medication in patients with autoimmune rheumatic diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA).The study aims to evaluate how the investigational medication affects the body, focusing on safety and how well it is tolerated by participants. Researchers …
This study investigates the safety and immune response of a vaccine for adults with moderate to severe acne. The purpose of this study is to evaluate how safe the vaccine is and how well it works in creating an immune response. The study will explore different doses to find the …
This study investigates the safety and effectiveness of a one-time injection for people with Geographic Atrophy related to Age-related Macular Degeneration. The study focuses on assessing how well the investigational injection works and its safety for participants. Researchers aim to gather data on the treatment's impact on vision over time.Who …
